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11/25/2021 8:04:31 AM | Browse: 45 | Download: 42
Publication Name World Journal of Gastroenterology
Manuscript ID 69548
Country/Territory Poland
Received
2021-07-04 17:01
Peer-Review Started
2021-07-04 17:06
To Make the First Decision
Return for Revision
2021-07-13 23:59
Revised
2021-07-14 22:50
Second Decision
2021-09-07 03:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-09-08 18:25
Articles in Press
2021-09-08 18:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-11-13 16:08
Typeset the Manuscript
2021-11-24 02:41
Publish the Manuscript Online
2021-11-25 07:42
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Systematic Reviews
Article Title Proton pump inhibitors and colorectal cancer: A systematic review
Manuscript Source Unsolicited Manuscript
All Author List Agastya Patel, Piotr Spychalski, Magdalena Antoszewska, Jaroslaw Regula and Jarek Kobiela
Funding Agency and Grant Number
Corresponding Author Jarek Kobiela, MD, PhD, Assistant Professor, Department of General, Endocrine and Transplant Surgery, Medical University of Gdansk, Marii Skłodowskiej-Curie 3a, Gdansk 80-210, Poland. grasper@tlen.pl
Key Words Colorectal cancer; Proton pump inhibitor; Carcinogenesis; Cancer epidemiology; Capecitabine; Translational medicine
Core Tip Proton pump inhibitors (PPI) are a widely, often inappropriately, used class of drugs. Through various mechanism, they are suspected to increase risk of gastrointestinal cancers, including colorectal cancer (CRC). The aim of this review is to summarize entirely of existing literature on the effect of PPI on CRC. The review assess basic research studies to identify mechanisms at play in this relationship, observational studies to determine if a causal association exists between PPI use and CRC incidence, and clinical studies to examine if PPI use during chemotherapy influences treatment efficacy and oncological outcomes.
Publish Date 2021-11-25 07:42
Citation Patel A, Spychalski P, Antoszewska M, Regula J, Kobiela J. Proton pump inhibitors and colorectal cancer: A systematic review. World J Gastroenterol 2021; 27(44): 7716-7733
URL https://www.wjgnet.com/1007-9327/full/v27/i44/7716.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i44.7716
Full Article (PDF) WJG-27-7716.pdf
Full Article (Word) WJG-27-7716.docx
Manuscript File 69548_Auto_Edited-Webster J-Clear.docx
Answering Reviewers 69548-Answering reviewers.pdf
Audio Core Tip 69548-Audio core tip.m4a
Biostatistics Review Certificate 69548-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 69548-Conflict-of-interest statement.pdf
Copyright License Agreement 69548-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 69548-Language certificate.pdf
Supplementary Material 69548-Supplementary material.pdf
Peer-review Report 69548-Peer-review(s).pdf
Scientific Misconduct Check 69548-Bing-Wang JJ-2.png
Scientific Editor Work List 69548-Scientific editor work list.pdf