Publication Name	World Journal of Transplantation
Manuscript ID	70166
Country	United Kingdom

Received	2021-07-26 15:58
Peer-Review Started	2021-07-26 16:00
To Make the First Decision
Return for Revision	2021-10-27 00:42
Revised	2021-12-08 08:20
Second Decision	2022-01-06 03:33
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-01-06 19:05
Articles in Press	2022-01-06 19:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-01-11 07:34
Publish the Manuscript Online	2022-01-12 07:13

ISSN	2220-3230 (online)
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Category	Transplantation
Manuscript Type	Case Report
Article Title	Is de novo membranous nephropathy suggestive of alloimmunity in renal transplantation? A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Prakash I Darji, Himanshu A Patel, Bhavya P Darji, Ajay Sharma and Ahmed Halawa
Funding Agency and Grant Number
Corresponding Author	Ahmed Halawa, FRCS (Gen Surg), MD, MSc, Surgeon, Department of Transplantation, Sheffield Teaching Hospitals, Glossop Rd, Sheffield S10 2JF, United Kingdom. ahmed.halawa@liverpool.ac.uk
Key Words	Post-transplant nephrotic syndrome; Recurrent membranous nephropathy; Secondary membranous nephropathy; Alloimmunity; Cryptic antigens; Case report
Core Tip	This is a case presentation of a patient who developed post-transplant nephrotic syndrome 3 mo after transplantation and was diagnosed with de novo membranous nephropathy (MN). He had received a well-matched living donor kidney. According to the literature, the most common causes of de novo MN include secondary causes and antibody mediated injury, which we ruled out. This patient was treated with increased dosage of tacrolimus and an angiotensin converting enzyme inhibitor, which resulted in a good recovery. We favoured a new concept of pathogenesis of de novo MN, which requires the identification of the causative antigens.
Publish Date	2022-01-12 07:13
Citation	Darji PI, Patel HA, Darji BP, Sharma A, Halawa A. Is de novo membranous nephropathy suggestive of alloimmunity in renal transplantation? A case report. World J Transplant 2022; 12(1): 15-20
URL	https://www.wjgnet.com/2220-3230/full/v12/i1/15.htm
DOI	2022; 12(1): 15-20 URL: https://www.wjgnet.com/2220-3230/full/v12/i1/15.htm DOI: https://dx.doi.org/10.5500/wjt.v12.i1.15

Full Article (PDF)	WJT-12-15.pdf
Full Article (Word)	WJT-12-15.docx
Manuscript File	70166_Auto_Edited.docx
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Peer-review Report	70166-Peer-review(s).pdf
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Scientific Editor Work List	70166-Scientific editor work list .pdf