Publication Name	World Journal of Gastroenterology
Manuscript ID	72735
Country	China

Received	2021-10-26 07:18
Peer-Review Started	2021-10-26 07:20
First Decision by Editorial Office Director	2021-12-27 02:12
Return for Revision	2021-12-27 02:12
Revised	2022-01-10 00:37
Publication Fee Transferred
Second Decision by Editor	2022-04-11 02:06
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2022-04-21 18:06
Articles in Press	2022-04-21 18:06
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-05-18 05:54
Publish the Manuscript Online	2022-05-27 11:37

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Long noncoding RNA TNFRSF10A-AS1 promotes colorectal cancer through upregulation of HuR
Manuscript Source	Unsolicited Manuscript
All Author List	Dan-Dan Wang, Dong-Lei Sun, Shao-Peng Yang, Jia Song, Meng-Yao Wu, Wei-Wei Niu, Mei Song and Xiao-Lan Zhang
Funding Agency and Grant Number
Corresponding Author	Xiao-Lan Zhang, MD, PhD, Chief Physician, Department of Gastroenterology, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Shijiazhuang 050000, Hebei Province, China. xiaolanzh@126.com
Key Words	Colorectal cancer; Long noncoding RNA; TNFRSF10A-AS1; miR-3121-3p; HuR
Core Tip	TNFRSF10A-AS1 was upregulated in colorectal cancer (CRC) tumor tissues and cell lines, and it was positively correlated with tumor grade and size in patients with CRC. In addition, TNFRSF10A-AS1 facilitated CRC growth and metastasis. Mechanistically, TNFRSF10A-AS1 was predominantly found in the cytoplasm of CRC cell lines and upregulated the level of the downstream target, HuR, by sponging miR-3121-3p, thereby further promoting colorectal tumorigenesis and progression.
Publish Date	2022-05-27 11:37
Citation	Wang DD, Sun DL, Yang SP, Song J, Wu MY, Niu WW, Song M, Zhang XL. Long noncoding RNA TNFRSF10A-AS1 promotes colorectal cancer through upregulation of HuR. World J Gastroenterol 2022; 28(20): 2184-2200
URL	https://www.wjgnet.com/1007-9327/full/v28/i20/2184.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i20.2184

Full Article (PDF)	WJG-28-2184.pdf
Full Article (Word)	WJG-28-2184.docx
Manuscript File	72735_Auto_Edited.docx
Answering Reviewers	72735-Answering reviewers.pdf
Audio Core Tip	72735-Audio core tip.m4a
Biostatistics Review Certificate	72735-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	72735-Conflict-of-interest statement.pdf
Copyright License Agreement	72735-Copyright license agreement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	72735-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	72735-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	72735-Language certificate.pdf
Peer-review Report	72735-Peer-review(s).pdf
Scientific Misconduct Check	72735-Bing-Chen YL-2.png
Scientific Editor Work List	72735-Scientific editor work list.pdf
CrossCheck Report	72735-CrossCheck report.pdf