| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Evidence-Based Medicine |
| Article Title |
Simple scoring system for predicting cirrhosis in nonalcoholic fatty liver disease
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Takaomi Kessoku, Yuji Ogawa, Masato Yoneda, Kento Imajo, Yoshio Sumida, Yuichiro Eguchi, Hideki Fujii, Hideyuki Hyogo, Masafumi Ono, Yasuaki Suzuki, Takumi Kawaguchi, Kazuaki Chayama, Saiyu Tanaka, Kazuma Fujimoto, Keizo Anzai, Toshiji Saibara, Michio Sata, Yoshito Itoh, Atsushi Nakajima and Takeshi Okanoue; Japan Study Group of NAFLD (JSG-NAFLD) |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Masato Yoneda, MD, PhD, Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, Japan. dryoneda@yahoo.co.jp |
| Key Words |
Nonalcoholic fatty liver disease; Cirrhosis; Fibrosis; Platelet; Albumin; Alanine aminotransferase ratio |
| Core Tip |
Nonalcoholic fatty liver disease (NAFLD) is an important cause of chronic and progressive liver injury. We aimed to develop a simple noninvasive scoring system for predicting liver cirrhosis in NAFLD patients. These three variables were combined in an unweighted sum [platelet count = 1 point, serum albumin = 1 point, aminotransferase (AST)/alanine aminotransferase (ALT) ratio = 1 point] to form an easily calculated composite score, called the PLALA (platelet, albumin, AST/ALT ratio) score. The diagnosis of PLALA ≥ 2 had sufficient accuracy for detecting liver cirrhosis in NAFLD patients. The PLALA score may be an ideal scoring system for detecting cirrhosis in NAFLD patients. |
| Publish Date |
2014-08-07 10:34 |
| Citation |
Kessoku T, Ogawa Y, Yoneda M, Imajo K, Sumida Y, Eguchi Y, Fujii H, Hyogo H, Ono M, Suzuki Y, Kawaguchi T, Chayama K, Tanaka S, Fujimoto K, Anzai K, Saibara T, Sata M, Itoh Y, Nakajima A, Okanoue T; Japan Study Group of NAFLD (JSG-NAFLD). Simple scoring system for predicting cirrhosis in nonalcoholic fatty liver disease. World J Gastroenterol 2014; 20(29): 10108-10114 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i29/10108.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i29.10108 |
