| ISSN |
2220-3192 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Minireviews |
| Article Title |
Botanical, chemical, and pharmacological characteristics of Lomatogonium rotatum: A review
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li-Li Dai, Rong-Gui Eni, Ming-Hai Fu and Gen-Na Ba |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81803845 |
| Natural Science Foundation of Inner Mongolia Autonomous Region |
2018MS08040 |
| Construction Project of "Inner Mongolia Autonomous Region Mongolian Medicine and Food Source Protection and Utilization Innovation Team" |
190301 |
| Graduate Research Project of Inner Mongolia Minzu University |
NMDBS1901 |
|
| Corresponding Author |
Gen-Na Ba, PhD, Professor, School of Mongolian Medicine, Inner Mongolia Minzu University, No. 996 Xilamulun Street, Horqin District, Tongliao 028000, Inner Mongolia Autonomous Region, China. bagenna@126.com |
| Key Words |
Mongolian medicine; Lomatogonium rotatum; Chemical composition; Pharmacological action; Research progress |
| Core Tip |
As a highly distinctive Mongolian medicinal herb, Lomatogonium rotatum (L. rotatum) Fries ex Nym is traditionally used to prevent and treat liver and gall diseases. However, its clinical application value and further development are limited by strict requirements on its growing environment, high demand for medicinal materials, decrease in wild resources, and insufficient scientific and technological availability in ethnic minority areas. Currently, a total of 38 compounds have been isolated and identified from L. rotatum Fries ex Nym, with flavonoids, xanthones, and terpenoids being the main metabolites. Pharmacological studies have mainly focused on hepatitis, liver injury, and weight loss, but mechanisms of pharmacological activity remain elusive and further comprehensive in vivo and in vivo experimental designs are needed to elucidate. |
| Publish Date |
2022-06-16 05:34 |
| Citation |
Dai LL, Eni RG, Fu MH, Ba GN. Botanical, chemical, and pharmacological characteristics of Lomatogonium rotatum: A Review. World J Pharmacol 2022; 11(2): 6-15 |
| URL |
https://www.wjgnet.com/2220-3192/full/v11/i2/6.htm |
| DOI |
https://dx.doi.org/10.5497/wjp.v11.i2.6 |
