| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Intestinal microbiome changes in an infant with right atrial isomerism and recurrent necrotizing enterocolitis: A case report and review of literature
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Aleksandra Kaplina, Ekaterina Zaikova, Artem Ivanov, Yulia Volkova, Tatiana Alkhova, Vladimir Nikiforov, Alexander Latypov, Marina Khavkina, Tatiana Fedoseeva, Tatiana Pervunina, Yulia Skorobogatova, Svetlana Volkova, Vladimir Ulyantsev, Olga Kalinina, Stanislav Sitkin and Natalia Petrova |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Ministry of Science and Higher Education of the Russian Federation |
075-15-2020-901 |
|
| Corresponding Author |
Stanislav Sitkin, MD, PhD, Associate Professor, Senior Researcher, Epigenetics and Metagenomics Group, Institute of Perinatology and Pediatrics, Almazov National Medical Research Centre, Akkuratova street, 2, St. Petersburg 197341, Russia. drsitkin@gmail.com |
| Key Words |
Necrotizing enterocolitis; Congenital heart disease; Ivemark syndrome; Heterotaxy; Right atrial isomerism; Intestinal microbiome; Case report |
| Core Tip |
Right atrial isomerism is associated with severe congenital heart disease, abnormal arrangement of internal organs, and asplenia/spleen hypoplasia. Infants with right atrial isomerism palliated with the systemic-to-pulmonary shunt have a “diastolic steal” of mesenteric blood flow, which increases the risk of necrotizing enterocolitis (NEC). The role of the microbiome in cardiogenic NEC remains unclear. This case report highlights possible interactions between dynamic changes in the fecal microbiome before and after cardiac surgery and development of recurrent NEC, based on hemodynamic changes, mesenterial perfusion, and antibacterial treatment in an asplenic infant with right atrial isomerism who underwent palliative cardiac surgery. |
| Publish Date |
2022-09-29 09:17 |
| Citation |
Kaplina A, Zaikova E, Ivanov A, Volkova Y, Alkhova T, Nikiforov V, Latypov A, Khavkina M, Fedoseeva T, Pervunina T, Skorobogatova Y, Volkova S, Ulyantsev V, Kalinina O, Sitkin S, Petrova N. Intestinal microbiome changes in an infant with right atrial isomerism and recurrent necrotizing enterocolitis: A case report and review of literature. World J Clin Cases 2022; 10(29): 10583-10599 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i29/10583.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i29.10583 |
