Publication Name	World Journal of Methodology
Manuscript ID	76138
Country	India

Received	2022-03-05 05:43
Peer-Review Started	2022-03-05 05:45
First Decision by Editorial Office Director	2022-06-16 08:52
Return for Revision	2022-06-16 08:52
Revised	2022-06-29 09:57
Publication Fee Transferred
Second Decision by Editor	2022-08-29 04:00
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2022-08-31 05:13
Articles in Press	2022-08-31 05:13
Edit the Manuscript by Language Editor	2022-08-22 16:51
Typeset the Manuscript	2022-09-13 02:42
Publish the Manuscript Online	2022-09-16 10:39

ISSN	2222-0682 (online)
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Category	Biochemistry & Molecular Biology
Manuscript Type	Systematic Reviews
Article Title	Growth differentiation factor 15 as an emerging novel biomarker in SARS-CoV-2 infection
Manuscript Source	Invited Manuscript
All Author List	Deepak Parchwani, Sagar Dholariya, CDS Katoch and Ragini Singh
Funding Agency and Grant Number
Corresponding Author	Sagar Dholariya, MD, Assistant Professor, Department of Biochemistry, All India Institute of Medical Sciences, Jamnagar Road, Khandheri, Rajkot 360001, Gujarat, India. drsagar.dholariya@gmail.com
Key Words	SARS-CoV-2; Growth differentiation factor 15; Biomarker; Risk-stratification; Prognosis
Core Tip	Growth differentiation factor (GDF)-15 levels are higher in hospitalized patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and higher levels are associated with disease severity, viremia and hypoxemia. The consistent increase in the concentration of GDF-15 during a hospital stay is associated with worse outcomes. Hence, serial monitoring of GDF-15 concentrations may provide useful prognostic value for hospitalized patients with SARS-CoV-2. GDF-15 appears to be involved in the underlying pathophysiology, laying the foundation for a novel therapeutic approach for SARS-CoV-2.
Publish Date	2022-09-16 10:39
Citation	Parchwani D, Dholariya S, Katoch C, Singh R. Growth differentiation factor 15 as an emerging novel biomarker in SARS-CoV-2 infection. World J Methodol 2022; 12(5): 438-447
URL	https://www.wjgnet.com/2222-0682/full/v12/i5/438.htm
DOI	https://dx.doi.org/10.5662/wjm.v12.i5.438

Full Article (PDF)	WJM-12-438.pdf
Full Article (Word)	WJM-12-438.docx
Manuscript File	76138_Auto_Edited-LM.docx
Answering Reviewers	76138-Answering reviewers.pdf
Audio Core Tip	76138-Audio core tip.aac
Biostatistics Review Certificate	76138-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	76138-Conflict-of-interest statement.pdf
Copyright License Agreement	76138-Copyright license agreement.pdf
Peer-review Report	76138-Peer-review(s).pdf
Scientific Misconduct Check	76138-Bing-Liu JH-2.jpg
Scientific Misconduct Check	76138-CrossCheck.jpg
Scientific Editor Work List	76138-Scientific editor work list.pdf
CrossCheck Report	76138-CrossCheck report.pdf