Publication Name	World Journal of Cardiology
Manuscript ID	76298
Country	Greece

Received	2022-03-11 07:13
Peer-Review Started	2022-03-11 07:16
To Make the First Decision
Return for Revision	2022-05-31 00:17
Revised	2022-06-09 10:42
Second Decision	2022-07-06 08:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-07-11 19:23
Articles in Press	2022-07-11 19:23
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-06-28 23:53
Typeset the Manuscript	2022-07-13 08:11
Publish the Manuscript Online	2022-07-20 02:45

ISSN	1949-8462 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Letter to the Editor
Article Title	Heart failure with reduced, mildly reduced, or preserved left ventricular ejection fraction: Has reasoning been lost?
Manuscript Source	Invited Manuscript
All Author List	Andrew Xanthopoulos, Grigorios Giamouzis, John Skoularigis and Filippos Triposkiadis
Funding Agency and Grant Number
Corresponding Author	Andrew Xanthopoulos, FACC, MD, PhD, Doctor, Department of Cardiology, University Hospital of Larissa, Mezourlo, Larissa 411 10, Greece. andrewvxanth@gmail.com
Key Words	Arbitrary; Cut off; Guidelines; Limitations; Normal left ventricular ejection fraction range; Phenotypic persistence
Core Tip	Left ventricular ejection fraction (LVEF) has been consistently used for the diagnosis, classification, and management of heart failure (HF) over the last three decades. HF is classified as HF with reduced LVEF, HF with midrange or mildly reduced LVEF, and HF with preserved LVEF using arbitrary, continuously changing LVEF cutoffs. A prerequisite for using this terminology is knowledge of the LVEF normal range, which is lacking and may lead to erroneous conclusions, especially at the higher end of the LVEF spectrum.
Publish Date	2022-07-20 02:45
Citation	Xanthopoulos A, Giamouzis G, Skoularigis J, Triposkiadis F. Heart failure with reduced, mildly reduced, or preserved left ventricular ejection fraction: Has reasoning been lost? World J Cardiol 2022; 14(7): 438-445
URL	https://www.wjgnet.com/1949-8462/full/v14/i7/438.htm
DOI	https://dx.doi.org/10.4330/wjc.v14.i7.438

Full Article (PDF)	WJC-14-438.pdf
Full Article (Word)	WJC-14-438.docx
Manuscript File	76298_Auto_Edited-HZ-Filipodia-LS.docx
Answering Reviewers	76298-Answering reviewers.pdf
Audio Core Tip	76298-Audio core tip.mp4
Conflict-of-Interest Disclosure Form	76298-Conflict-of-interest statement.pdf
Copyright License Agreement	76298-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	76298-Language certificate.pdf
Peer-review Report	76298-Peer-review(s).pdf
Scientific Editor Work List	76298-Scientific editor work list.pdf