BPG is committed to discovery and dissemination of knowledge
Featured Articles
9/9/2022 1:12:42 PM | Browse: 38 | Download: 49
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 76336
Country/Territory United Arab Emirates
Received
2022-03-16 00:22
Peer-Review Started
2022-03-16 00:24
To Make the First Decision
Return for Revision
2022-04-17 03:22
Revised
2022-05-05 16:06
Second Decision
2022-07-21 03:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-07-26 19:06
Articles in Press
2022-07-26 19:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-08-26 01:30
Publish the Manuscript Online
2022-09-09 12:48
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Review
Article Title Emerging role of caldesmon in cancer: A potential biomarker for colorectal cancer and other cancers
Manuscript Source Invited Manuscript
All Author List Alya R Alnuaimi, Vidhya A Nair, Lara J Bou Malhab, Eman Abu-Gharbieh, Anu Vinod Ranade, Gianfranco Pintus, Mohamad Hamad, Hauke Busch, Jutta Kirfel, Rifat Hamoudi and Wael M Abdel-Rahman
Funding Agency and Grant Number
Corresponding Author Wael M Abdel-Rahman, MD, PhD, Professor, Department of Medical Laboratory Sciences, University of Sharjah, University City, Sharjah 27272, United Arab Emirates. whassan@sharjah.ac.ae
Key Words Bladder cancer; CALD1; Caldesmon; Chemoresistance; Colorectal cancer; Gastric cancer; Glioma; Epithelial to mesenchymal transition; Invasion; Metastasis
Core Tip The actin-binding protein caldesmon (CaD) plays an important role in cancer development, metastasis, and resistance to chemotherapy. CaD has emerged as a significant player in carcinogenesis, as it features many cancer hallmarks, including epithelial mesenchymal transition, angiogenesis, and immune evasion. Interestingly, CaD undergoes selective tumor-specific splicing, and the resulting isoforms are generally not expressed in normal tissues. These data qualify CaD as an attractive candidate for targeted therapy in addition to its role in the diagnosis and prognosis of cancer.
Publish Date 2022-09-09 12:48
Citation Alnuaimi AR, Nair VA, Malhab LJB, Abu-Gharbieh E, Ranade AV, Pintus G, Hamad M, Busch H, Kirfel J, Hamoudi R, Abdel-Rahman WM. Emerging role of caldesmon in cancer: A potential biomarker for colorectal cancer and other cancers. World J Gastrointest Oncol 2022; 14(9): 1637-1653
URL https://www.wjgnet.com/1948-5204/full/v14/i9/1637.htm
DOI https://dx.doi.org/10.4251/wjgo.v14.i9.1637
Full Article (PDF) WJGO-14-1637.pdf
Full Article (Word) WJGO-14-1637.docx
Manuscript File 76336_Author_Edited-LM.docx
Answering Reviewers 76336-Answering reviewers.pdf
Audio Core Tip 76336-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 76336-Conflict-of-interest statement.pdf
Copyright License Agreement 76336-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 76336-Language certificate.pdf
Supplementary Material 76336-Supplementary material.pdf
Peer-review Report 76336-Peer-review(s).pdf
Scientific Misconduct Check 76336-Bing-Wang JJ-2.png
Scientific Editor Work List 76336-Scientific editor work list.pdf