Publication Name	World Journal of Clinical Oncology
Manuscript ID	76882
Country	Brazil

Received	2022-04-08 16:50
Peer-Review Started	2022-04-08 16:52
First Decision by Editorial Office Director	2022-05-12 08:48
Return for Revision	2022-05-12 08:48
Revised	2022-06-14 18:52
Publication Fee Transferred
Second Decision by Editor	2022-07-11 02:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2022-07-11 21:27
Articles in Press	2022-07-11 21:27
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-07-28 07:08
Publish the Manuscript Online	2022-08-23 09:54

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Transplantation
Manuscript Type	Retrospective Cohort Study
Article Title	Propensity-matched analysis of patients with intrahepatic cholangiocarcinoma or mixed hepatocellular-cholangiocarcinoma and hepatocellular carcinoma undergoing a liver transplant
Manuscript Source	Unsolicited Manuscript
All Author List	Ajacio Bandeira de Mello Brandão, Santiago Rodriguez, Alfeu de Medeiros Fleck Jr, Claudio Augusto Marroni, Mário B Wagner, Alex Hörbe, Matheus V Fernandes, Carlos TS Cerski and Gabriela Perdomo Coral
Funding Agency and Grant Number
Corresponding Author	Ajacio Bandeira de Mello Brandão, PhD, Academic Research, Graduate Program in Medicine: Hepatology, School of Medicine, Universidade Federal de Ciências da Saúde de Porto Alegre, R. Eng. Álvaro Nunes Pereira, 400/402, Porto Alegre 90050170, RS, Brazil. ajaciob@gmail.com
Key Words	Cholangiocarcinoma; Hepatocellular carcinoma; Liver; Prognosis; Recurrence; Survival analysis; Transplantation
Core Tip	This retrospective cohort study analyzes the outcomes of patients undergoing liver transplantation (LT) with a presumptive diagnosis of hepatocellular carcinoma (HCC) in which explant analysis identified that they actually had intrahepatic cholangiocarcinoma (ICC) or mixed hepatocellular cholangiocarcinoma (HCC-CC). Propensity score matching was used to analyze tumor recurrence, overall mortality, and recurrence-free survival in LT recipients with pathologically confirmed ICC or HCC-CC matched 1:8 to those with HCC. Patients with ICC have worse outcomes than patients undergoing LT for HCC, even when matched for explant pathology. Outcomes did not differ significantly between patients with HCC-CC and patients with HCC.
Publish Date	2022-08-23 09:54
Citation	Brandão ABM, Rodriguez S, Fleck Jr AM, Marroni CA, Wagner MB, Hörbe A, Fernandes MV, Cerski CT, Coral GP. Propensity-matched analysis of patients with intrahepatic cholangiocarcinoma or mixed hepatocellular-cholangiocarcinoma and hepatocellular carcinoma undergoing a liver transplant. World J Clin Oncol 2022; 13(8): 689-702
URL	https://www.wjgnet.com/2218-4333/full/v13/i8/688.htm
DOI	https://dx.doi.org/10.5306/wjco.v13.i8.688

Full Article (PDF)	WJCO-13-688.pdf
Full Article (Word)	WJCO-13-688.docx
Manuscript File	76882_Auto_Edited_LM.docx
Answering Reviewers	76882-Answering reviewers.pdf
Audio Core Tip	76882-Audio core tip.ogg
Biostatistics Review Certificate	76882-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	76882-Conflict-of-interest statement.pdf
Copyright License Agreement	76882-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	76882-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	76882-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	76882-Language certificate.pdf
Peer-review Report	76882-Peer-review(s).pdf
Scientific Misconduct Check	76882-Bing-Wang LL-2.png
Scientific Editor Work List	76882-Scientific editor work list.pdf
CrossCheck Report	76882-CrossCheck report.pdf