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1/4/2023 12:20:52 PM | Browse: 311 | Download: 1039
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Received |
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2022-07-22 17:36 |
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Peer-Review Started |
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2022-07-22 17:37 |
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To Make the First Decision |
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Return for Revision |
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2022-09-26 10:25 |
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Revised |
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2022-10-06 16:46 |
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Second Decision |
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2022-12-05 03:18 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-12-06 20:42 |
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Articles in Press |
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2022-12-06 20:42 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-12-16 07:12 |
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Typeset the Manuscript |
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2023-01-03 06:20 |
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Publish the Manuscript Online |
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2023-01-04 10:43 |
| ISSN |
2218-6204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, General & Internal |
| Manuscript Type |
Case Report |
| Article Title |
Venous thromboembolism prophylaxis of a patient with MYH-9 related disease and COVID-19 infection: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Bei Jiang, Michelle Hartzell, Stephen Yu, Muhammad Masab and Laurel Lyckholm |
| Funding Agency and Grant Number |
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| Corresponding Author |
Bei Jiang, MD, Doctor, Doctor, Hematology and Oncology , West Virginia University , 1 medical drive , Morgantown, 26505, United States. bei.jiang@hsc.wvu.edu |
| Key Words |
Venous thromboembolism event; Prophylaxis; MYH9-related disease; Anticoagulation in inherited platelet disorder; Low molecular heparin; COVID-19; Case report |
| Core Tip |
May-Hegglin anomaly is one of several autosomal dominant disorders described as MYH9 mutation-related diseases (MYH9-RD). The MYH9 gene encodes the heavy chain of non-muscle myosin. A mutation in the MYH9 gene leads to interruption of megakaryocyte migration toward the vasculature and impairs proplatelet release in the marrow, therefore causing macrothrombocytopenia and mild to moderate bleeding tendency. It may be misdiagnosed as treatment-resistant immune thrombocytopenia. Severity of bleeding in patients with MYH9-RD is related to the degree of thrombocytopenia and to physical properties of the large platelets. MYH9-RD is not an absolute contraindication to anticoagulation or antiplatelet agents. If a patient with MYH9-RD presents with an indication for anticoagulation, such as coronavirus disease 2019 infection, one must take a careful history of previous bleeding episodes, and weigh bleeding risk against the risk of thrombosis. |
| Publish Date |
2023-01-04 10:43 |
| Citation |
Jiang B, Hartzell M, Yu S, Masab M, Lyckholm L. Venous thromboembolism prophylaxis of a patient with MYH-9 related disease and COVID-19 infection: A case report. World J Hematol 2023; 10(1): 1-8 |
| URL |
https://www.wjgnet.com/2218-6204/full/v10/i1/1.htm |
| DOI |
https://dx.doi.org/10.5315/wjh.v10.i1.1 |
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