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2/21/2023 3:57:12 AM | Browse: 226 | Download: 709
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Received |
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2022-09-20 09:24 |
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Peer-Review Started |
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2022-09-20 09:27 |
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To Make the First Decision |
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Return for Revision |
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2022-11-29 03:09 |
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Revised |
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2022-12-13 13:31 |
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Second Decision |
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2023-02-07 03:31 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-02-07 06:37 |
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Articles in Press |
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2023-02-07 06:37 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-01-20 02:09 |
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Typeset the Manuscript |
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2023-02-16 14:32 |
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Publish the Manuscript Online |
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2023-02-21 03:35 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Therapeutic challenge for immunotherapy targeting cold colorectal cancer: A narrative review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Shi-Xun Ma, Li Li, Hui Cai, Tian-Kang Guo and Lei-Sheng Zhang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Key Laboratory of Gastrointestinal Tumor Diagnosis and Treatment of National Health and Health Commission |
2019PT320005 |
| the National Natural Science Foundation of China |
82260031 |
| Key Laboratory of Molecular Diagnosis and Precision Therapy of Surgical Tumors in Gansu Province |
18JR2RA033 |
| Gansu Provincial Key Talent Project of Gansu Provincial Party Committee Organization Department |
2020RCXM076 |
| Lanzhou Science and Technology Development Guidance Program |
2019-ZD-102 |
| Natural Science Foundation of Gansu Province |
21JR11RA186, 20JR10RA415 |
| Gansu Provincial Hospital Intra-Hospital Research Fund Project |
21GSSYB-8, 20GSSY5-2 |
| The 2021 Central-Guided Local Science and Technology Development Fund |
ZYYDDFFZZJ-1 |
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| Corresponding Author |
Lei-Sheng Zhang, PhD, Assistant Professor, Department of General Surgery, Gansu Provincial Hospital, 204 West Donggang R.D., Lanzhou 730000, Gansu Province, China. leisheng_zhang@163.com |
| Key Words |
Cold colorectal cancer; Immunotherapy; Tumor microenvironment; Immune targets; Immune cells |
| Core Tip |
Advanced colorectal tumors are poorly treated, and immunotherapy has improved these patients’ outcomes. However, cold colorectal tumors are less likely to trigger a robust immune response and tend to suppress it. To address this phenomenon, we discuss the role of the tumor microenvironment, immune targets, and immune cells in the treatment of cold colorectal tumors. |
| Publish Date |
2023-02-21 03:35 |
| Citation |
Ma SX, Li L, Cai H, Guo TK, Zhang LS. Therapeutic challenge for immunotherapy targeting cold colorectal cancer: A narrative review. World J Clin Oncol 2023; 14(2): 81-88 |
| URL |
https://www.wjgnet.com/2218-4333/full/v14/i2/81.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v14.i2.81 |
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