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6/1/2023 1:29:01 PM | Browse: 117 | Download: 307
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Received |
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2023-03-05 04:53 |
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Peer-Review Started |
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2023-03-05 04:55 |
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To Make the First Decision |
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Return for Revision |
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2023-04-03 04:18 |
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Revised |
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2023-04-14 08:34 |
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Second Decision |
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2023-04-28 03:33 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2023-04-28 17:29 |
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Articles in Press |
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2023-04-28 17:29 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-05-26 05:49 |
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Publish the Manuscript Online |
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2023-06-01 13:04 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Ineffective esophageal motility is associated with acute rejection after lung transplantation independent of gastroesophageal reflux
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Wai-Kit Lo, Brent Hiramoto, Hilary J Goldberg, Nirmal Sharma and Walter W Chan |
| Funding Agency and Grant Number |
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| Corresponding Author |
Walter W Chan, AGAF, FACG, MD, Associate Professor, Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, United States. wwchan@bwh.harvard.edu |
| Key Words |
Ineffective esophageal motility; Esophageal hypomotility; Esophageal manometry; Gastroesophageal reflux disease; Lung transplantation; Acute rejection |
| Core Tip |
While gastroesophageal reflux (GER) has been associated with poorer outcomes after lung transplant, the impact of esophageal dysmotility remains unclear. Our study found that ineffective esophageal motility identified on pre-transplant esophageal manometry was independently associated with increased acute allograft rejection, even after adjusting for GER. This suggests that esophageal hypomotility may increase the risk of poor lung transplant outcome independent of GER. Routine esophageal function assessment should be considered in the peri-transplant evaluation of lung transplant patients to identify, risk stratify, and more effectively manage esophageal dysfunction in such patients at risk of poorer outcomes. |
| Publish Date |
2023-06-01 13:04 |
| Citation |
Lo WK, Hiramoto B, Goldberg HJ, Sharma N, Chan WW. Ineffective esophageal motility is associated with acute rejection after lung transplantation independent of gastroesophageal reflux. World J Gastroenterol 2023; 29(21): 3292-3301 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i21/3292.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i21.3292 |
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