Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	82794
Country	United States

Received	2022-12-29 02:20
Peer-Review Started	2022-12-29 02:23
To Make the First Decision
Return for Revision	2023-01-31 08:48
Revised	2023-02-09 03:26
Second Decision	2023-03-21 03:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-03-21 07:43
Articles in Press	2023-03-21 07:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-04-24 06:32
Publish the Manuscript Online	2023-06-08 09:24

ISSN	2219-2808 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Pediatrics
Manuscript Type	Minireviews
Article Title	Hirschsprung's disease associated enterocolitis: A comprehensive review
Manuscript Source	Invited Manuscript
All Author List	Eric M Gershon, Leonel Rodriguez and Ricardo A Arbizu
Funding Agency and Grant Number
Corresponding Author	Ricardo A Arbizu, MD, MS, Assistant Professor, Pediatric Gastroenterology, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, United States. ricardo.arbizu@yale.edu
Key Words	Hirschsprung’s; Enterocolitis; Pathogenesis; Microbiome; Dysbiosis; Dysmotility; Treatment
Core Tip	Hirschsprung’s disease associated enterocolitis (HAEC) is an inflammatory complication of Hirschsprung’s disease (HSCR) with variable degrees of severity. It is important for pediatric providers to be aware of the signs and symptoms of HAEC as it can affect patients before or after corrective surgery. The pathogenesis of HAEC is multifactorial and previous and ongoing studies continue to improve our knowledge of this potentially fatal complication of HSCR and will ultimately allow clinicians to provide personalized care for these patients. In the meantime, current preventive measures and treatment guidelines have helped decrease the morbidity and mortality associated with HAEC.
Publish Date	2023-06-08 09:24
Citation	Gershon EM, Rodriguez L, Arbizu RA. Hirschsprung's disease associated enterocolitis: A comprehensive review. World J Clin Pediatr 2023; 12(3): 68-76
URL	https://www.wjgnet.com/2219-2808/full/v12/i3/68.htm
DOI	https://dx.doi.org/10.5409/wjcp.v12.i3.68

Full Article (PDF)	WJCP-12-68-with-cover.pdf
Full Article (Word)	WJCP-12-68.docx
Manuscript File	82794_Auto_Edited-JLW.docx
Answering Reviewers	82794-Answering reviewers.pdf
Audio Core Tip	82794-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	82794-Conflict-of-interest statement.pdf
Copyright License Agreement	82794-Copyright license agreement.pdf
Peer-review Report	82794-Peer-review(s).pdf
Scientific Misconduct Check	82794-Bing-Ma YJ-2.jpg
Scientific Editor Work List	82794-Scientific editor work list.pdf