Publication Name	World Journal of Immunology
Manuscript ID	85467
Country	India

Received	2023-04-28 14:23
Peer-Review Started	2023-04-28 14:25
To Make the First Decision
Return for Revision	2023-06-26 02:24
Revised	2023-07-06 09:57
Second Decision	2023-07-27 02:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-07-27 07:56
Articles in Press	2023-07-27 07:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-08-07 02:48
Publish the Manuscript Online	2023-08-14 08:39

ISSN	2219-2824 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Medicine, Research & Experimental
Manuscript Type	Minireviews
Article Title	Stem cell-like memory T cells: Role in viral infections and autoimmunity
Manuscript Source	Invited Manuscript
All Author List	Meenakshi Sachdeva, Shivangi Taneja and Naresh Sachdeva
Funding Agency and Grant Number
Corresponding Author	Naresh Sachdeva, MSc, PhD, Professor, Department of Endocrinology, Post Graduate Institute of Medical Education and Research (PGIMER), Sector-12, Chandigarh 160012, India. sachdeva.naresh@pgimer.edu.in
Key Words	Stem cell-like memory T cells; Viral infections; Autoimmune diseases; Effector T cells; Memory T cells
Core Tip	This article discusses the contrasting roles of stem cell-like memory T (TSCM) cells during chronic viral infections and autoimmune diseases. During chronic viral infections, such as human immunodeficiency virus-1, the TSCM cells serve as reservoirs for latent viruses, which can be activated to make them susceptible to cytotoxic T cell responses. However, during acute viral infections, the TSCM cells have the ability to replenish the diminished effector T cell population. In autoimmune diseases, like type-1 diabetes, these cells contribute to the disease pathogenesis by persistent generation of autoreactive effector T cells. A better understanding of the key signaling pathways and mediators regulating TSCM cells could lead to novel approaches to target or manipulate these cells for immunotherapeutic applications.
Publish Date	2023-08-14 08:39
Citation	Sachdeva M, Taneja S, Sachdeva N. Stem cell-like memory T cells: Role in viral infections and autoimmunity. World J Immunol 2023; 13(2): 11-22
URL	https://www.wjgnet.com/2219-2824/full/v13/i2/11.htm
DOI	https://dx.doi.org/10.5411/wji.v13.i2.11

Full Article (PDF)	WJI-13-11-with-cover.pdf
Full Article (Word)	WJI-13-11.docx
Manuscript File	85467_Auto_Edited-JLW.docx
Answering Reviewers	85467-Answering reviewers.pdf
Audio Core Tip	85467-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	85467-Conflict-of-interest statement.pdf
Copyright License Agreement	85467-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	85467-Language certificate.pdf
Peer-review Report	85467-Peer-review(s).pdf
Scientific Misconduct Check	85467-Bing-Chen YL-2.png
Scientific Editor Work List	85467-Scientific editor work list.pdf