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9/20/2023 6:29:05 AM | Browse: 235 | Download: 532
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Received |
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2023-06-21 15:01 |
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Peer-Review Started |
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2023-06-21 21:38 |
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To Make the First Decision |
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Return for Revision |
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2023-08-10 07:19 |
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Revised |
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2023-08-17 15:46 |
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Second Decision |
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2023-08-28 03:07 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-08-29 09:34 |
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Articles in Press |
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2023-08-29 09:34 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-09-17 09:46 |
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Publish the Manuscript Online |
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2023-09-20 04:15 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Minireviews |
| Article Title |
Advances in drug resistance of triple negative breast cancer caused by pregnane X receptor
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Zhou-Zhou Rao, Zhong-Wen Tang and Jie Wen |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science project of Hunan Provincial Health Commission |
No. B202304089304 |
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| Corresponding Author |
Jie Wen, PhD, Assistant Professor, Department of Pediatric Orthopedics, Hunan Provincial People’s Hospital, the First Affiliated Hospital of Hunan Normal University, No. 61 West Jiefang Rd, Changsha 410013, Hunan Province, China. cashwj@qq.com |
| Key Words |
Triple-negative breast cancer; Pregnane X receptor; Drug resistance; Cytochrome P450; Uridinediphosphate glucuronyl transferases; Glutathione transferases; ATP-binding cassette transporter |
| Core Tip |
Treatment of triple-negative breast cancer (TNBC) is a difficult problem in the clinical treatment of breast cancer. It is a very urgent task to explore the mechanism of TNBC resistance in basic breast cancer research. Pregnane X receptor (PXR) is a nuclear receptor whose main biological function is to participate in the metabolism, transport and clearance of allobiological agents in PXR. This reviews synthesized the important role of PXR in the process of high drug resistance to TNBC chemotherapeutic drugs and related research progress. |
| Publish Date |
2023-09-20 04:15 |
| Citation |
Rao ZZ, Tang ZW, Wen J. Advances in drug resistance of triple negative breast cancer caused by pregnane X receptor. World J Clin Oncol 2023; 14(9): 335-342 |
| URL |
https://www.wjgnet.com/2218-4333/full/v14/i9/335.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v14.i9.335 |
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