Publication Name	World Journal of Clinical Oncology
Manuscript ID	87074
Country	United States

Received	2023-07-26 00:40
Peer-Review Started	2023-07-26 02:20
To Make the First Decision
Return for Revision	2023-09-04 07:27
Revised	2023-09-20 18:04
Second Decision	2023-10-16 02:18
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-10-23 07:13
Articles in Press	2023-10-23 07:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-11-16 07:28
Publish the Manuscript Online	2023-11-22 04:14

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Case Report
Article Title	Calcitriol induced hypercalcemia - a rare phenomenon in lung cancer: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Amulya Prakash, Farhan Khalid, Ahmad Alalwan, Husam Bader, Doantrang Du and Trishala Meghal
Funding Agency and Grant Number
Corresponding Author	Farhan Khalid, MD, Chief Physician, Department of Internal Medicine, Monmouth Medical Center, 200 Second Avenue, Long Branch, NJ 07740, United States. farhan.khalid.md@gmail.com
Key Words	Hypercalcemia associated malignancy; Lung cancer; Denosumab; Calcitriol; Vitamin D; Case report
Core Tip	Our case report illuminates a rare mechanism of hypercalcemia in lung malignancies, characterized by elevated calcitriol. Despite its rarity, it sheds light on the pathophysiology of hypercalcemia in solid malignancies, notably lung cancers. To the best of our knowledge, this is the first documented case in medical literature to present this mechanism. Moreover, the successful management of this condition with bisphosphonates highlights the potential efficacy of this treatment approach for future cases involving similar symptoms. By emphasizing this novel observation, our report contributes to the expanding body of knowledge regarding hypercalcemia in lung cancers and paves the way for the development of novel therapeutic strategies for the treatment of such cases.
Publish Date	2023-11-22 04:14
Citation	Prakash A, Khalid F, Alalwan A, Bader H, Du D, Meghal T. Calcitriol induced hypercalcemia - a rare phenomenon in lung cancer: A case report. World J Clin Oncol 2023; 14(11): 544-548
URL	https://www.wjgnet.com/2218-4333/full/v14/i11/544.htm
DOI	https://dx.doi.org/10.5306/wjco.v14.i11.544

Full Article (PDF)	WJCO-14-544-with-cover.pdf
Full Article (Word)	WJCO-14-544.docx
CARE Checklist–2016	87074-CARE Checklist (2016).pdf
Manuscript File	87074_Auto_Edited-JLW.docx
Answering Reviewers	87074-Answering reviewers.pdf
Audio Core Tip	87074-Audio core tip.mp4
Conflict-of-Interest Disclosure Form	87074-Conflict-of-interest statement.pdf
Copyright License Agreement	87074-Copyright license agreement.pdf
Signed Consent for Treatment Form(s) or Document(s)	87074-Informed consent statement.pdf
Peer-review Report	87074-Peer-review(s).pdf
Scientific Misconduct Check	87074-Bing-Wang JJ-2.png
Scientific Editor Work List	87074-Scientific editor work list.pdf