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12/26/2023 12:35:11 PM | Browse: 108 | Download: 257
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Received |
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2023-07-28 02:11 |
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Peer-Review Started |
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2023-07-28 02:13 |
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To Make the First Decision |
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Return for Revision |
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2023-09-27 18:28 |
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Revised |
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2023-11-06 19:15 |
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Second Decision |
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2023-11-30 02:48 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2023-11-30 06:18 |
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Articles in Press |
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2023-11-30 06:18 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-12-20 13:49 |
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Publish the Manuscript Online |
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2023-12-26 02:50 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Physiology |
| Manuscript Type |
Review |
| Article Title |
Stem cells and pain
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Matheus Deroco Veloso da Silva, Maiara Piva, Geovana Martelossi-Cebinelli, Mariana Stinglin Rosa Ribas, Beatriz Hoffmann Salles Bianchini, Olivia K Heintz, Rubia Casagrande and Waldiceu A Verri Jr |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Conselho Nacional de Desenvolvimento Científico e Tecnológico |
CNPq; #203112/2020-2 and #307852/2019-9 |
| Conselho Nacional de Desenvolvimento Científico e Tecnológico |
CNPq; #309633/2021-4 and #405027/2021-4 |
| Conselho Nacional de Desenvolvimento Científico e Tecnológico |
CNPq; #427946/2018-2 |
| PRONEX grant supported by SETI/Fundação Araucária and MCTI/CNPq, and Governo do Estado do Paraná |
#014/2017 |
| Fundação Araucária |
PBA/PROPPG 13/2021 agreements #276/2022-PBA |
| Fundação Araucária |
PBA/PROPPG 13/2021 agreements #250/2022-PBA |
| Financiadora de Estudos e Projetos-FINEP |
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| CAPES (finance code #001) |
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| Corresponding Author |
Waldiceu A Verri Jr, PhD, Associate Professor, Department of Pathology, Laboratory of Pain, Inflammation, Neuropathy and Cancer, Center of Biological Sciences, State University of Londrina, Rodovia Celso Garcia Cid/Pr 445 Km 380, Londrina 86057-970, Paraná, Brazil. waverri@uel.br |
| Key Words |
Inflammation; Neuropathy; Nociceptive; Pain; Pain treatment; Stem cells |
| Core Tip |
Since the discovery of stem cells (SCs), they have emerged from a distant dream into a routine therapeutic approach depending on the field. Nowadays, the use of SCs in pain management is mainly based on their anti-inflammatory capacities, releasing neurotrophic factors and providing cellular support to replace damaged neural cells. Evidence supports that SCs can influence nociceptor neuron sensitization building a foundation for the application of these versatile cells in the treatment of neuropathic and inflammatory pain. |
| Publish Date |
2023-12-26 02:50 |
| Citation |
Silva MDVD, Piva M, Martelossi-Cebinelli G, Stinglin Rosa Ribas M, Hoffmann Salles Bianchini B, K Heintz O, Casagrande R, Verri Jr WA. Stem cells and pain. World J Stem Cells 2023; 15(12): 1035-1062 |
| URL |
https://www.wjgnet.com/1948-0210/full/v15/i12/1035.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v15.i12.1035 |
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