| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Clinical and Translational Research |
| Article Title |
Elucidating the molecular basis of ATP-induced cell death in breast cancer: Construction a robust prognostic model
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hao-Ling Zhang, Sandai Doblin, Zhong-Wen Zhang, Zhi-Jing Song, Babu Dinesh, Yasser Tabana, Dahham Sabbar Saad, Mowaffaq Adam Ahmed Adam, Yong Wang, Wei Wang, Hao-Long Zhang, Sen Wu, Rui Zhao and Barakat Khaled |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81960877 |
| University Innovation Fund of Gansu Province |
2021A-076 |
| Gansu Province Science and Technology Plan (Innovation Base and Talent Plan) |
21JR7RA561 |
| Natural Science Foundation of Gansu Province |
21JR1RA267 |
| Natural Science Foundation of Gansu Province |
22JR5RA582 |
| Education Technology Innovation Project of Gansu Province |
2022A-067 |
| Innovation Fund of Higher Education of Gansu Province |
2023A-088 |
| Open Project of Key Laboratory of Dunhuang Medicine and Transformation of Ministry of Education |
DHYX21-07 |
| Open Project of Key Laboratory of Dunhuang Medicine and Transformation of Ministry of Education |
DHYX21-01 |
| Open Project of Key Laboratory of Dunhuang Medicine and Transformation of Ministry of Education |
DHYX22-05 |
| Gansu Province science and technology plan international cooperation field project |
23YFWA0005 |
|
| Corresponding Author |
Sandai Doblin, PhD, Professor, Department of Biomedical Sciences, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas, Penang 13200, Malaysia. doblin@usm.my |
| Key Words |
ATP-Induced Cell Death; mRNA; miRNA; Prognostic model; Breast cancer |
| Core Tip |
This study carefully developed and validated a prognostic model based on the intricately underlying genes associated with ATP-induced cell death. At the same time, we cleverly shaped a microRNA prognostic model that harmonizes with a gene-centric approach. This study comprehensively elucidates the complex molecular basis of ATP-induced breast cancer cell death, which not only opens up new avenues for potential therapeutic interventions, but also promotes an innovative paradigm in the field of personalized oncology. By enhancing our understanding of this complex cellular process, we anticipate that our research will facilitate the emergence of groundbreaking strategies that are transformative. |
| Publish Date |
2024-02-20 08:53 |
| Citation |
Zhang HL, Doblin S, Zhang ZW, Song ZJ, Dinesh B, Tabana Y, Saad DS, Adam Ahmed Adam M, Wang Y, Wang W, Zhang HL, Wu S, Zhao R, Khaled B. Elucidating the molecular basis of ATP-induced cell death in breast cancer: Construction a robust prognostic model. World J Clin Oncol 2024; 15(2): 208-242 |
| URL |
https://www.wjgnet.com/2218-4333/full/v15/i2/208.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v15.i2.208 |
