Publication Name	World Journal of Gastroenterology
Manuscript ID	88973
Country	Australia

Received	2023-10-17 10:22
Peer-Review Started	2023-10-17 10:24
To Make the First Decision
Return for Revision	2023-10-31 23:21
Revised	2023-11-10 00:54
Second Decision	2023-11-23 02:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-12-02 17:36
Articles in Press	2023-12-02 17:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-12-15 02:09
Publish the Manuscript Online	2023-12-19 02:09

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Liver decompensation after rapid weight loss from semaglutide in a patient with non-alcoholic steatohepatitis -associated cirrhosis
Manuscript Source	Unsolicited Manuscript
All Author List	Matthew Peverelle, Jonathan Ng, James Peverelle, Ryan D. Hirsch and Adam Testro
Funding Agency and Grant Number
Corresponding Author	Matthew Peverelle, MD, Doctor, Liver transplant unit, Austin Health, 145 Studley Rd, Heidelberg VIC 3084, Melbourne 3084, Australia. matthewpeverelle@gmail.com
Key Words	Semaglutide; Non-alcoholic steatohepatitis; Cirrhosis; Non-alcoholic steatohepatitis cirrhosis; Glucagon-like peptide 1 agonists; Weight loss
Core Tip	Patients with NASH cirrhosis who lose weight rapidly (approximately ≥ 1% of body weight per week) with semaglutide are at risk of liver decompensation. This complication requires the immediate cessation of semaglutide and aggressive nutritional rehabilitation with supplemental protein feeds and micronutrients. Restoration of lost weight can lead to liver recompensation; however, consideration of liver transplantation should be given to patients who fail to respond to treatment.
Publish Date	2023-12-19 02:09
Citation	Peverelle M, Ng J, Peverelle J, Hirsch RD, Testro A. Liver decompensation after rapid weight loss from semaglutide in a patient with non-alcoholic steatohepatitis -associated cirrhosis. World J Gastroenterol 2023; 29(47): 6165-6167
URL	https://www.wjgnet.com/1007-9327/full/v29/i47/6165.htm
DOI	https://dx.doi.org/10.3748/wjg.v29.i47.6165

Full Article (PDF)	WJG-29-6165-with-cover.pdf
Full Article (Word)	WJG-29-6165.docx
Manuscript File	88973_Auto_Edited-LM.docx
Answering Reviewers	88973-Answering reviewers.pdf
Audio Core Tip	88973-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	88973-Conflict-of-interest statement.pdf
Copyright License Agreement	88973-Copyright license agreement.pdf
Peer-review Report	88973-Peer-review(s).pdf
Scientific Misconduct Check	88973-Bing-Lin C-2.png
Scientific Editor Work List	88973-Scientific editor work list.pdf