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1/23/2024 11:00:46 AM | Browse: 161 | Download: 507
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Received |
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2023-10-26 20:38 |
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Peer-Review Started |
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2023-10-26 20:39 |
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To Make the First Decision |
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Return for Revision |
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2023-12-01 23:20 |
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Revised |
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2023-12-04 19:50 |
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Second Decision |
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2023-12-21 07:23 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-12-28 08:19 |
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Articles in Press |
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2023-12-28 08:19 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-01-18 07:03 |
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Publish the Manuscript Online |
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2024-01-23 09:31 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Virology |
| Manuscript Type |
Editorial |
| Article Title |
Molecular mechanisms underlying severe acute respiratory syndrome coronavirus-2 hepatotropism and liver damage
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jorge Quarleri and M Victoria Delpino |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Agencia Nacional de Promoción Científica y Tecnológica (PICTO-2021-COVID secuelas-00005 to JQ) |
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| Corresponding Author |
Jorge Quarleri, PhD, Adjunct Professor, Research Scientist, Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Universidad de Buenos Aires (UBA), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Paraguay 2155, Buenos Aires 1121, Argentina. quarleri@fmed.uba.ar |
| Key Words |
Severe acute respiratory syndrome coronavirus-2; COVID-19; Hepatotropism; Angiotensin-converting enzyme-2 |
| Core Tip |
The hepatotropism of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a growing concern amid the Coronavirus Disease 2019 (COVID-19) pandemic. Despite its respiratory focus, the virus significantly affects various organs, notably the liver, leading to complications like inflammation, abnormal function tests, and, in severe cases, organ damage. This complex involvement worsens disease outcomes. Understanding the virus's interplay with the liver, mediated by the Angiotensin-converting enzyme-2 receptor, is crucial for tailored treatments. The liver's pivotal role in the immune response emphasizes the need to comprehend SARS-CoV-2 hepatotropism. Ongoing research is vital for uncovering mechanisms, clinical implications, and effective strategies in managing COVID-19 patients with liver involvement. |
| Publish Date |
2024-01-23 09:31 |
| Citation |
Quarleri J, Delpino MV. Molecular mechanisms underlying severe acute respiratory syndrome coronavirus-2 hepatotropism and liver damage. World J Hepatol 2024; 16(1): 1-11 |
| URL |
https://www.wjgnet.com/1948-5182/full/v16/i1/1.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v16.i1.1 |
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