ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Permissions |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Case Report |
Article Title |
Pathologically successful conversion hepatectomy for advanced giant hepatocellular carcinoma after multidisciplinary therapy: A case report and review of literature
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Ju-Hang Chu, Lu-Yao Huang, Ya-Ru Wang, Jun Li, Shi-Long Han, Hao Xi, Wen-Xue Gao, Ying-Yu Cui and Ming-Ping Qian |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Shanghai Hospital Development Center Foundation |
SHDC2022CRS033 |
|
Corresponding Author |
Ying-Yu Cui, PhD, Associate Professor, Editor-in-Chief, Teacher, Department of Cell Biology, Institute of Medical Genetics, Key Laboratory of Arrhythmias of the Ministry of Education of China (Tongji University), Tongji University School of Medicine, No. 500 Zhennan Road, Putuo District, Shanghai 200331, China. yycui@tongji.edu.cn |
Key Words |
Hepatocellular therapy; Conversion hepatectomy; Interventional therapy; Epclusa; Lenvatinib; Sintilimab; Case report |
Core Tip |
The present study describes the excellent efficacy of conversion therapy including interventional therapy, anti-hepatitis C virus therapy, and immunotargeted therapy for advanced giant hepatocellular carcinoma (HCC). After 21 months of conversion therapy, the patient underwent surgical resection completely and the postoperative pathology suggested a complete response. In summary, conversion therapy is a promising treatment option for unresectable HCC patients. |
Publish Date |
2024-04-11 02:23 |
Citation |
Chu JH, Huang LY, Wang YR, Li J, Han SL, Xi H, Gao WX, Cui YY, Qian MP. Pathologically successful conversion hepatectomy for advanced giant hepatocellular carcinoma after multidisciplinary therapy: A case report and review of literature. World J Gastrointest Oncol 2024; 16(4): 1647-1659 |
URL |
https://www.wjgnet.com/1948-5204/full/v16/i4/1647.htm |
DOI |
https://dx.doi.org/10.4251/wjgo.v16.i4.1647 |