Publication Name	World Journal of Virology
Manuscript ID	90384
Country	Argentina

Received	2023-12-01 19:23
Peer-Review Started	2023-12-01 19:23
To Make the First Decision
Return for Revision	2023-12-07 08:01
Revised	2023-12-07 16:00
Second Decision	2024-01-05 02:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-01-05 07:45
Articles in Press	2024-01-05 07:45
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-01-04 02:07
Typeset the Manuscript	2024-02-18 07:24
Publish the Manuscript Online	2024-03-11 14:44

ISSN	2220-3249 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Editorial
Article Title	Perilipin 2 inhibits replication of hepatitis B virus deoxyribonucleic acid by regulating autophagy under high-fat conditions
Manuscript Source	Invited Manuscript
All Author List	M Victoria Delpino and Jorge Quarleri
Funding Agency and Grant Number
Corresponding Author	M Victoria Delpino, PhD, Research Scientist, Instituto de Investigaciones Biomédicas en Retrovirus y Sida, Universidad de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas, Paraguay 2155 Piso 11, Buenos Aires 1121, Argentina. mdelpino@ffyb.uba.ar
Key Words	Perilipin 2; Hepatitis B virus; Non-alcoholic fatty liver disease; Liver; Autophagy
Core Tip	Hepatitis B virus (HBV) infection poses a global health concern without a definitive cure. This study delves into the complex interplay between lipid metabolism and HBV replication. It reveals that heightened lipid metabolism may exert an inhibitory effect on HBV replication. Specifically, increased fatty acids lead to the accumulation of lipid droplets and the upregulation of perilipin 2 in hepatocytes. This, in turn, inhibits autophagy and subsequently hinders HBV replication.
Publish Date	2024-03-11 14:44
Citation	Delpino MV, Quarleri J. Perilipin 2 inhibits replication of hepatitis B virus deoxyribonucleic acid by regulating autophagy under high-fat conditions. World J Virol 2024; 13(1): 90384
URL	https://www.wjgnet.com/2220-3249/full/v13/i1/90384.htm
DOI	https://dx.doi.org/10.5501/wjv.v13.i1.90384

Full Article (PDF)	WJV-13-90384-with-cover.pdf
Full Article (Word)	WJV-13-90384.docx
Manuscript File	90384_Auto_Edited-LJH_WangTQ-JLW.docx
Answering Reviewers	90384-Answering reviewers.pdf
Audio Core Tip	90384-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	90384-Conflict-of-interest statement.pdf
Copyright License Agreement	90384-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	90384-Language certificate.pdf
Peer-review Report	90384-Peer-review(s).pdf
Scientific Misconduct Check	90384-Bing-Liu JH-2.png
Scientific Misconduct Check	90384-CrossCheck.png
Scientific Editor Work List	90384-Scientific editor work list.pdf