Publication Name	World Journal of Gastroenterology
Manuscript ID	90465
Country	Spain

Received	2023-12-04 19:43
Peer-Review Started	2023-12-04 19:43
To Make the First Decision
Return for Revision	2024-01-23 05:26
Revised	2024-02-01 13:24
Second Decision	2024-03-08 02:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-03-08 06:23
Articles in Press	2024-03-08 06:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-03-18 01:41
Publish the Manuscript Online	2024-03-28 12:17

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Review
Article Title	Liquid biopsy for gastric cancer: Techniques, applications, and future directions
Manuscript Source	Invited Manuscript
All Author List	Cristina Díaz del Arco, M Jesús Fernández Aceñero and Luis Ortega Medina
Funding Agency and Grant Number
Corresponding Author	Cristina Díaz del Arco, MD, PhD, Associate Professor, Staff Physician, Department of Surgical Pathology, Health Research Institute of the Hospital Clínico San Carlos, Hospital Clínico San Carlos, c/Profesor Martín Lagos s/n, Madrid 28040, Spain. crisdelarco@gmail.com
Key Words	Liquid biopsy; Gastric cancer; Circulating tumor cells; Cell-free DNA; Circulating tumor DNA; Molecular
Core Tip	Liquid biopsy (LB) has the potential to revolutionize cancer diagnostics, offering reduced invasiveness and improved understanding of tumor heterogeneity. Going beyond examining circulating tumor cells and cell-free DNA in blood, LB studies now explore a variety of structures and non-blood samples. Despite advancements in LB for tumor detection, prognostic assessment and treatment guidance, challenges remain, including complex and expensive techniques, lack of standardization, and suboptimal scientific evidence. In the context of gastric cancer, LB represents a promising approach, especially in advanced stages. This review navigates through LB intricacies, emphasizing its benefits while urging for future improvements to achieve clinical impact.
Publish Date	2024-03-28 12:17
Citation	Díaz del Arco C, Fernández Aceñero MJ, Ortega Medina L. Liquid biopsy for gastric cancer: Techniques, applications, and future directions. World J Gastroenterol 2024; 30(12): 1680-1705
URL	https://www.wjgnet.com/1007-9327/full/v30/i12/1680.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i12.1680

Full Article (PDF)	WJG-30-1680-with-cover.pdf
Manuscript File	90465_Auto_Edited-YJP.docx
Answering Reviewers	90465-Answering reviewers.pdf
Audio Core Tip	90465-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	90465-Conflict-of-interest statement.pdf
Copyright License Agreement	90465-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	90465-Language certificate.pdf
Supplementary Material	90465-Supplementary material.pdf
Peer-review Report	90465-Peer-review(s).pdf
Scientific Misconduct Check	90465-Bing-Chen YL-2.png
Scientific Editor Work List	90465-Scientific editor work list.pdf
CrossCheck Report	90465-CrossCheck report.pdf