Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	91521
Country	United States

Received	2024-01-01 04:49
Peer-Review Started	2024-01-01 04:49
To Make the First Decision
Return for Revision	2024-01-25 20:59
Revised	2024-02-03 03:36
Second Decision	2024-03-25 01:21
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-03-25 02:50
Articles in Press	2024-03-25 02:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-04-11 06:16
Publish the Manuscript Online	2024-04-22 11:03

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Pathology
Manuscript Type	Minireviews
Article Title	Blastomas of the digestive system in adults: A review
Manuscript Source	Invited Manuscript
All Author List	Yu Liu, Tony El Jabbour, Jonathan Somma, Yukihiro Nakanishi, Saverio Ligato, Hwajeong Lee and Zhi-Yan Fu
Funding Agency and Grant Number
Corresponding Author	Zhi-Yan Fu, MD, Attending Doctor, Department of Pathology, LSU Health Sciences Center School of Medicine, 1901 Perdido St, New Orleans, LA 70112, United States. zfu@lsuhsc.edu
Key Words	Adult blastomas; Gastroblastoma; Hepatoblastoma; Pancreatoblastoma; Digestive system
Core Tip	Adult digestive system blastomas, including gastroblastoma, hepatoblastoma, and pancreatoblastoma, are rare neoplasms with less than a hundred cases reported for each type. They have nonspecific clinical presentations and imaging findings. Gastroblastoma diagnosis hinges on biphasic histology and the Metastasis-Associated Lung Adenocarcinoma Transcript 1 - Glioma-Associated Oncogene Homolog 1 (MALAT1-GLI1) gene fusion. Hepatoblastoma recapitulates the different embryological stages of liver development and can be epithelial or mixed epitheliomesenchymal. Pancreatoblastoma demonstrates multidirectional differentiation and contains squamoid nests. Surgical resection is the primary treatment for these tumors with adjuvant chemotherapy or radiotherapy in some cases. Prognoses vary, with gastroblastoma typically having better post-surgical outcomes. In contrast, hepatoblastoma and pancreatoblastoma frequently recur and metastasize.
Publish Date	2024-04-22 11:03
Citation	Liu Y, El Jabbour T, Somma J, Nakanishi Y, Ligato S, Lee H, Fu ZY. Blastomas of the digestive system in adults: A review. World J Gastrointest Surg 2024; 16(4): 1030-1042
URL	https://www.wjgnet.com/1948-9366/full/v16/i4/1030.htm
DOI	https://dx.doi.org/10.4240/wjgs.v16.i4.1030

Full Article (PDF)	WJGS-16-1030-with-cover.pdf
Manuscript File	91521_Auto_Edited-YJP.docx
Answering Reviewers	91521-Answering reviewers.pdf
Audio Core Tip	91521-Audio core tip.wav
Conflict-of-Interest Disclosure Form	91521-Conflict-of-interest statement.pdf
Copyright License Agreement	91521-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	91521-Language certificate.pdf
Peer-review Report	91521-Peer-review(s).pdf
Scientific Misconduct Check	91521-Bing-Li L-2.png
Scientific Editor Work List	91521-Scientific editor work list.pdf
CrossCheck Report	91521-CrossCheck report.pdf
CrossCheck Report	91521-CrossCheck.png