Publication Name	World Journal of Gastroenterology
Manuscript ID	10079
Country	Japan

Received	2014-03-11 21:56
Peer-Review Started	2014-03-12 09:31
First Decision by Editorial Office Director
Return for Revision	2014-04-15 01:30
Revised	2014-04-22 20:05
Publication Fee Transferred
Second Decision by Editor	2014-07-25 09:22
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-07-25 09:46
Articles in Press	2014-07-25 09:56
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-09-22 16:15
Publish the Manuscript Online	2014-10-07 17:32

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Review
Article Title	Interventional treatment for unresectable hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Satoru Murata, Takahiko Mine, Fumie Sugihara, Daisuke Yasui, Hidenori Yamaguchi, Tatsuo Ueda, Shiro Onozawa and Shin-ichiro Kumita
Funding Agency and Grant Number
Corresponding Author	Satoru Murata, MD, PhD, Department of Radiology/Center for Advanced Medical Technology, Nippon Medical School, 1-1-5 Sendagi, Bunkyou-ku, Tokyo 113-8602, Japan. genji@nms.ac.jp
Key Words	Unresectable; Hepatocellular carcinoma; Intermediate-stage; Advanced-stage; Interventional
Core Tip	Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. Interventional treatments for intermediate-stage HCC patients such as transcatheter arterial chemoembolization (TACE), drug-eluting bead embolization, and radioembolization, continue to evolve, improving prognosis. However, advanced-stage HCC is typically treated only with sorafenib, with only a modest improvement in overall survival. More effective therapies such as combined TACE and radiotherapy, TACE with special techniques, and isolated hepatic perfusion have been studied extensively. This review summarizes data on published and important ongoing studies concerning interventional treatments for unresectable HCC and discusses technical improvements in these interventions, particularly for advanced-stage HCC.
Publish Date	2014-10-07 17:32
Citation	Murata S, Mine T, Sugihara F, Yasui D, Yamaguchi H, Ueda T, Onozawa S, Kumita S. Interventional treatment for unresectable hepatocellular carcinoma. World J Gastroenterol 2014; 20(37): 13453-13465
URL	http://www.wjgnet.com/1007-9327/full/v20/i37/13453.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i37.13453

Full Article (PDF)	WJG-20-13453.pdf
Full Article (Word)	WJG-20-13453.doc
Manuscript File	10079-Review.docx
Answering Reviewers	10079-Answering reviewers.pdf
Copyright License Agreement	10079-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	10079-Language certificate.pdf
Peer-review Report	10079-Peer review.pdf
Scientific Misconduct Check	10079-CrossCheck.JPG
Scientific Editor Work List	10079-Scientific editor work list.pdf