Publication Name	World Journal of Gastroenterology
Manuscript ID	10562
Country	China

Received	2014-04-07 12:42
Peer-Review Started	2014-04-07 12:50
To Make the First Decision	2014-05-20 11:11
Return for Revision	2014-05-20 11:47
Revised	2014-06-08 14:19
Second Decision	2014-06-26 17:13
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-06-26 17:14
Articles in Press	2014-06-26 17:46
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-07-08 16:41
Typeset the Manuscript	2014-10-26 20:39
Publish the Manuscript Online	2014-11-10 19:10

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Effects of baicalin in CD4 + CD29 + T cell subsets of ulcerative colitis patients
Manuscript Source	Unsolicited Manuscript
All Author List	Feng-Yan Yu, Shao-Gang Huang, Hai-Yan Zhang, Hua Ye, Hong-Gang Chi, Ying Zou, Ru-Xi Lv and Xue-Bao Zheng
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 30772701
Corresponding Author	Feng-Yan Yu, PhD, Traditional Chinese Medicine Institute Guangdong Medical College, Dalingshan Town Songshan Lake Park, No. 1, Metro Avenue, Dongguan 524023, Guangdong Province, China. yujoyce022@163.com
Key Words	Ulcerative colitis; Baicalin; CD4+CD29+; Cytokines; Nuclear factor-B
Core Tip	Ulcerative colitis is a kind of chronic and non-specific inflammatory bowel disease. Researchers believe that several distinguishing factors such as immune systems, genes and environment are likely necessary to result in ulcerative colitis (UC). The study here demonstrated that baicalin might be a potential immune inhibitor. It adjusted immune balance and relieved the inflammatory response caused by UC, probably by inhibiting the ratio of CD4+CD29+ cells and immunosuppressive pathways. Our results provide valuable information for further studies on the pathogenesis of UC and for the development of new drugs, and also provide a new view of studying T helper cell immune disorder-related diseases including UC.
Publish Date	2014-11-10 19:10
Citation	Yu FY, Huang SG, Zhang HY, Ye H, Chi HG, Zou Y, Lv RX, Zheng XB. Effects of baicalin in CD4 + CD29 + T cell subsets of ulcerative colitis patients. World J Gastroenterol 2014; 20(41): 15299-15309
URL	http://www.wjgnet.com/1007-9327/full/v20/i41/15299.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i41.15299

Full Article (PDF)	WJG-20-15299.pdf
Full Article (Word)	WJG-20-15299.doc
Manuscript File	10562-Review.docx
Answering Reviewers	10562-Answering reviewers.pdf
Copyright License Agreement	10562-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	10562-Language certificate.pdf
Peer-review Report	10562-Peer review.pdf
Scientific Misconduct Check	10562-CorssCheck.jpg
Scientific Editor Work List	10562-Scientific editor work list.pdf