Publication Name	World Journal of Nephrology
Manuscript ID	10668
Country	United States

Received	2014-04-13 15:24
Peer-Review Started	2014-04-13 17:02
To Make the First Decision	2014-06-06 10:58
Return for Revision	2014-06-10 09:31
Revised	2014-06-13 04:34
Second Decision	2014-07-29 09:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-07-29 10:00
Articles in Press	2014-07-29 10:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-09-30 16:25
Publish the Manuscript Online	2014-10-19 20:47

ISSN	2220-6124 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, General & Internal
Manuscript Type	Review
Article Title	Chronic kidney disease prediction is an inexact science: The concept of “progressors” and “nonprogressors”
Manuscript Source	Invited Manuscript
All Author List	Macaulay Amechi Chukwukadibia Onuigbo and Nneoma Agbasi
Funding Agency and Grant Number
Corresponding Author	Macaulay Amechi Chukwukadibia Onuigbo, MD, MSc, FWACP, FASN, MBA, Department of Nephrology, Mayo Clinic Health System, 1221 Whipple Street, Eau Claire, WI 54702, Unites States. onuigbo.macaulay@mayo.edu
Key Words	Acute kidney injury; Chronic kidney disease; Chronic kidney disease staging; Estimated glomerular filtration rate; End stage renal disease; National Kidney Foundation Kidney Disease Outcomes Quality Initiative; Renal replacement therapy; Serum creatinine; Syndrome of late onset renal failure from angiotensin blockade; Syndrome of rapid onset end stage renal disease
Core Tip	In 2002, the National Kidney Foundation established a novel chronic kidney disease (CKD) staging paradigm. In 2012, the authoritative United States Preventative Task Force questioned the validity of asymptomatic CKD screening. The American Society of Nephrology and the American College of Physicians have opposite recommendations regarding this controversy. We examined the evidence-base and limitations of CKD staging. Furthermore, we show clinical evidence of pitfalls of the current CKD staging model and the failings of current CKD prediction models. We called for more research into CKD to end stage renal disease translations including the impact of acute kidney injury on this continuum. CKD care and prognostication must be individualized.
Publish Date	2014-10-19 20:47
Citation	Onuigbo MAC, Agbasi N. Chronic kidney disease prediction is an inexact science: The concept of “progressors” and “nonprogressors”. World J Nephrol 2014; 3(3): 31-49
URL	http://www.wjgnet.com/2220-6124/full/v3/i3/31.htm
DOI	http://dx.doi.org/10.5527/wjn.v3.i3.31

Full Article (PDF)	WJN-3-31.pdf
Full Article (Word)	WJN-3-31.doc
Manuscript File	10668-Review.docx
Answering Reviewers	10668-Answering reviewers.pdf
Copyright License Agreement	10668-Copyright assignment.pdf
Peer-review Report	10668-Peer review(s).pdf
Scientific Misconduct Check	10668-CrossCheck.jpg
Scientific Editor Work List	10668-Scientific editor work list.pdf