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Articles Published Processes
3/9/2015 3:58:00 PM | Browse: 1241 | Download: 1543
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Received |
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2014-04-16 09:13 |
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Peer-Review Started |
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2014-04-16 16:12 |
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To Make the First Decision |
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2014-05-13 20:05 |
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Return for Revision |
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2014-05-21 08:28 |
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Revised |
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2014-10-07 00:00 |
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Second Decision |
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2014-11-19 09:07 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-11-19 09:08 |
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Articles in Press |
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2014-11-19 09:40 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-02-26 10:47 |
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Publish the Manuscript Online |
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2015-03-09 15:58 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
N-acetylcysteine treats intravenous amiodarone induced liver injury
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Matthew L Mudalel, Kartikeya P Dave, James P Hummel and Steven F Solga |
| Funding Agency and Grant Number |
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| Corresponding Author |
Steven F Solga, MD, Chief of Gastroenterology, Department of Medicine, Division of Gastroenteorlogy, St. Luke’s University Hospital and Temple School of Medicine, 701 Ostrum St. Suite 604A, Bethlehem, PA 18015, United States. stevesolga@gmail.com |
| Key Words |
N-acetylcysteine; Amiodarone; Drug induced liver injury; Liver enzymes; Pathogenesis |
| Core Tip |
Intravenous (IV) amiodarone drug induced liver injury (DILI) is uncommon, and difficult to distinguish from ischemic hepatitis or congestive hepatopathy. Further, the pathophysiology is uncertain. IV N-acetylcysteine (NAC) is often used empirically as a treatment for idiopathic hepatitis or DILI. We report a case of rapid improvement of liver enzymes in a suspected case of IV amiodarone DILI with IV NAC, suggesting at least some shared features between the pathogenic mechanisms of the former and the therapeutic actions of the latter. |
| Publish Date |
2015-03-09 15:58 |
| Citation |
Mudalel ML, Dave KP, Hummel JP, Solga SF. N-acetylcysteine treats intravenous amiodarone induced liver injury. World J Gastroenterol 2015; 21(9): 2816-2819 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i9/2816.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i9.2816 |
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