Publication Name	World Journal of Clinical Urology
Manuscript ID	10900
Country	Germany

Received	2014-04-25 09:51
Peer-Review Started	2014-04-29 09:23
To Make the First Decision	2014-05-14 13:36
Return for Revision	2014-05-20 20:55
Revised	2014-06-29 05:44
Second Decision	2014-08-29 19:06
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-08-29 19:16
Articles in Press	2014-08-29 19:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-11-17 08:46
Publish the Manuscript Online	2014-11-19 17:43

ISSN	2219-2816 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Urology & Nephrology
Manuscript Type	Review
Article Title	Spontaneous regression of renal cell carcinoma: Reality or myth?
Manuscript Source	Invited Manuscript
All Author List	Matthias Maruschke, Aristotelis G Anastasiadis and Oliver W Hakenberg
Funding Agency and Grant Number
Corresponding Author	Matthias Maruschke, MD, Department of Urology, University of Rostock, Ernst-Heydemann-Strasse 6, 18055 Rostock, Germany. matthias.maruschke@med.uni-rostock.de
Key Words	Renal cell carcinoma; Spontaneous regression; Primary renal cell carcinoma; Metastatic renal cell carcinoma lesions; Cytoreductive nephrectomy
Core Tip	Renal cell carcinoma (RCC) is an aggressive malignancy, which, from an immunological point of view, is highly variable. In the era of immunotherapy for metastatic RCC with interferon or interleukin it was always emphasized that spontaneous remissions of RCC, although comparatively rare, do occur and support the use of immunological therapies in metastatic disease. However, we suspected that this frequently cited occurrence of spontaneous remissions is more legend than reality. We therefore undertook an extensive literature search and included reports from the last 100 years in order to evaluate the scientific evidence describing spontaneous regressions of primary or metastatic RCC.
Publish Date	2014-11-19 17:43
Citation	Maruschke M, Anastasiadis AG, Hakenberg OW. Spontaneous regression of renal cell carcinoma: Reality or myth? World J Clin Urol 2014; 3(3): 201-208
URL	http://www.wjgnet.com/2219-2816/full/v3/i3/201.htm
DOI	http://dx.doi.org/10.5410/wjcu.v3.i3.201

Full Article (PDF)	WJCU-3-201.pdf
Full Article (Word)	WJCU-3-201.doc
Manuscript File	10900-Review.docx
Answering Reviewers	10900-Answering reviewers.pdf
Copyright License Agreement	10900-Copyright assignment.pdf
Peer-review Report	10900-Peer review(s).pdf
Scientific Misconduct Check	10900-CrossCheck.jpg
Scientific Editor Work List	10900-Scientific editor work list.pdf