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Articles Published Processes
1/27/2015 3:33:00 PM | Browse: 1459 | Download: 1387
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Received |
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2014-05-08 20:53 |
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Peer-Review Started |
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2014-05-11 12:48 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2014-06-12 09:43 |
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Revised |
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Publication Fee Transferred |
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Second Decision by Editor |
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2014-08-28 09:51 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2014-08-28 10:09 |
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Articles in Press |
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2014-08-28 10:48 |
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Edit the Manuscript by Language Editor |
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2014-10-08 18:03 |
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Typeset the Manuscript |
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2015-01-16 15:56 |
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Publish the Manuscript Online |
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2015-01-27 15:33 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Autobiography |
| Article Title |
Weichang’an and 5-fluorouracil suppresses colorectal cancer in a mouse model
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li Tao, Jin-Kun Yang, Ying Gu, Xin Zhou, Ai-Guang Zhao, Jian Zheng and Ying-Jie Zhu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Research Fund of Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine |
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| Budgetary Scientific Research Project |
2011JW33 |
| Young Talent Scientific Research Project |
20134y141 |
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| Corresponding Author |
Jin-Kun Yang, Chief physician, Professor, Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, No. 725, South Wanping Road, Shanghai 200032, China. yangjinkun131229@163.com |
| Key Words |
Colorectal cancer; Hepatic metastasis; Weichang’an formula; Orthotopic transplant nude mouse model; Chemotherapeutics 5-fluorouracil |
| Core Tip |
In this study, the anti-colon cancer activity of Weichang’an (WCA), a Chinese herbal medicine, was assessed in an orthotopic transplantation nude mouse model. Combination of WCA with 5-fluorouracil inhibited orthotopic tumor growth and hepatic me?tastases. Decreased expression of ?-catenin and me?talloproteinase-7, which are crucial proteins modulating tumor aggression, may be important for the anti-tumor properties of WCA. |
| Publish Date |
2015-01-27 15:33 |
| Citation |
Tao L, Yang JK, Gu Y, Zhou X, Zhao AG, Zheng J, Zhu YJ. Weichang’an and 5-fluorouracil suppresses colorectal cancer in a mouse model. World J Gastroenterol 2015; 21(4): 1125-1139 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i4/1125.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i4.1125 |
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