ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Case Report |
Article Title |
Successful treatment of conversion chemotherapy for initially unresectable synchronous colorectal liver metastasis
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Kenta Baba, Akihiko Oshita, Mohei Kohyama, Satoshi Inoue, Yuta Kuroo, Takuro Yamaguchi, Hiroyuki Nakamura, Yoichi Sugiyama, Tatsuya Tazaki, Masaru Sasaki, Yuji Imamura, Yutaka Daimaru, Hideki Ohdan and Atsushi Nakamitsu |
Funding Agency and Grant Number |
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Corresponding Author |
Akihiko Oshita, MD, PhD, Department of Surgery, JA Hiroshima General Hospital, 1-3-3 Jigozen, Hatsuka-ichi, Hiroshima 738-8503, Japan. oshita-akihiko@umin.ac.jp |
Key Words |
Initially unresectable; Colorectal liver metastasis; Conversion chemotherapy; Cetuximab; Percutaneous transhepatic portal vein embolization |
Core Tip |
A 72-year-old woman with a sigmoid colon cancer and a synchronous colorectal liver metastasis (CRLM) was referred to our hospital. The metastatic lesion was diagnosed to be initially unresectable. After she had undergone laparoscopic sigmoidectomy for the original tumor, she consequently had 6 courses of modified 5-fluorouracil, leucovorin, and oxaliplatin plus cetuximab, resulting in conversion chemotherapy. Preoperative percutaneous transhepatic portal vein embolization was performed to secure the future remnant liver volume. Finally, a right hemihepatectomy was successfully performed. The postoperative course was uneventful. She had no recurrence for 18 mo. This multidisciplinary strategy could contribute in facilitating curative hepatic resection for initially unresectable CRLM. |
Publish Date |
2015-02-11 17:56 |
Citation |
Baba K, Oshita A, Kohyama M, Inoue S, Kuroo Y, Yamaguchi T, Nakamura H, Sugiyama Y, Tazaki T, Sasaki M, Imamura Y, Daimaru Y, Ohdan H, Nakamitsu A. successful treatment of conversion chemotherapy for initially unresectable synchronous colorectal liver metastasis. World J Gastroenterol 2015; 21(6): 1982-1988 |
URL |
http://www.wjgnet.com/1007-9327/full/v21/i6/1982.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v21.i6.1982 |