Publication Name	World Journal of Gastroenterology
Manuscript ID	11843
Country	Thailand

Received	2014-06-08 11:27
Peer-Review Started	2014-06-08 20:03
To Make the First Decision	2014-06-27 17:48
Return for Revision	2014-07-02 17:17
Revised	2014-07-30 00:00
Second Decision	2014-09-19 09:11
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-09-19 09:58
Articles in Press	2014-09-19 10:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-01-09 08:21
Publish the Manuscript Online	2015-01-20 20:12

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Deficient DNA mismatch repair is associated with favorable prognosis in Thai patients with sporadic colorectal cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Krittiya Korphaisarn, Ananya Pongpaibul, Chanin Limwongse, Ekkapong Roothumnong, Wipawi Klaisuban, Akarin Nimmannit, Artit Jinawath and Charuwan Akewanlop
Funding Agency and Grant Number	Funding Agency Grant Number Siriraj Research Development Fund 459/2554(EC2)
Corresponding Author	Charuwan Akewanlop, MD, Division of Medical Oncology, Department of Medicine, Faculty of Medicine Siriraj Hospital, 13th Floor Chalerm-Prakiat Building, Bangkok-noi, Bangkok 10700, Thailand. charuwan.ake@mahidol.ac.th
Key Words	Sporadic colorectal cancer; Mismatch repair; BRAF; Overall survival
Core Tip	This study is the first report of prevalence and outcome in sporadic colorectal cancer that habour deficient mismatch repair (dMMR) and BRAF gene mutation in Thai population. The prevalence of dMMR and BRAF V600E mutation was 15% and 11%, respectively. This study confirmed the favorable outcome in patients with dMMR tumors, which is consistent to the results of previous reports in Caucasian population. The method we used to detect BRAF mutation is allele specific polymerase chain reaction which has the highest sensitivity to detect this mutation when compared to previously reported methods
Publish Date	2015-01-20 20:12
Citation	Korphaisarn K, Pongpaibul A, Limwongse C, Roothumnong E, Klaisuban W, Nimmannit A, Jinawath A, Akewanlop C. Deficient DNA mismatch repair is associated with favorable prognosis in Thai patients with sporadic colorectal cancer. World J Gastroenterol 2015; 21(3): 926-934
URL	http://www.wjgnet.com/1007-9327/full/v21/i3/926.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i3.926

Full Article (PDF)	WJG-21-926.pdf
Full Article (Word)	WJG-21-926.doc
Manuscript File	11843-Review.docx
Answering Reviewers	11843-Answering reviewers.pdf
Copyright License Agreement	11843-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethics_Committee_20140607182115.pdf
Non-Native Speakers of English Editing Certificate	11843-Language certificate.pdf
Peer-review Report	11843-Peer review.pdf
Scientific Misconduct Check	11843-CorssCheck.jpg
Scientific Editor Work List	11843-Scientific editor work list.pdf