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Articles Published Processes
1/20/2015 9:10:00 PM | Browse: 914 | Download: 1184
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Received |
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2014-06-08 11:27 |
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Peer-Review Started |
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2014-06-08 20:03 |
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To Make the First Decision |
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2014-06-27 17:48 |
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Return for Revision |
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2014-07-02 17:17 |
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Revised |
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2014-07-30 00:00 |
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Second Decision |
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2014-09-19 09:11 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2014-09-19 09:58 |
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Articles in Press |
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2014-09-19 10:30 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-01-09 08:21 |
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Publish the Manuscript Online |
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2015-01-20 20:12 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Deficient DNA mismatch repair is associated with favorable prognosis in Thai patients with sporadic colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Krittiya Korphaisarn, Ananya Pongpaibul, Chanin Limwongse, Ekkapong Roothumnong, Wipawi Klaisuban, Akarin Nimmannit, Artit Jinawath and Charuwan Akewanlop |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Siriraj Research Development Fund |
459/2554(EC2) |
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| Corresponding Author |
Charuwan Akewanlop, MD, Division of Medical Oncology, Department of Medicine, Faculty of Medicine Siriraj Hospital, 13th Floor Chalerm-Prakiat Building, Bangkok-noi, Bangkok 10700, Thailand. charuwan.ake@mahidol.ac.th
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| Key Words |
Sporadic colorectal cancer; Mismatch repair; BRAF; Overall survival |
| Core Tip |
This study is the first report of prevalence and outcome in sporadic colorectal cancer that habour deficient mismatch repair (dMMR) and BRAF gene mutation in Thai population. The prevalence of dMMR and BRAF V600E mutation was 15% and 11%, respectively. This study confirmed the favorable outcome in patients with dMMR tumors, which is consistent to the results of previous reports in Caucasian population. The method we used to detect BRAF mutation is allele specific polymerase chain reaction which has the highest sensitivity to detect this mutation when compared to previously reported methods |
| Publish Date |
2015-01-20 20:12 |
| Citation |
Korphaisarn K, Pongpaibul A, Limwongse C, Roothumnong E, Klaisuban W, Nimmannit A, Jinawath A, Akewanlop C. Deficient DNA mismatch repair is associated with favorable prognosis in Thai patients with sporadic colorectal cancer. World J Gastroenterol 2015; 21(3): 926-934 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i3/926.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i3.926 |
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