Publication Name	World Journal of Gastroenterology
Manuscript ID	11940
Country	China

Received	2014-06-13 08:31
Peer-Review Started	2014-06-13 13:11
To Make the First Decision	2014-07-21 13:11
Return for Revision	2014-07-23 09:58
Revised	2014-08-03 12:47
Second Decision	2014-09-16 13:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-09-16 13:52
Articles in Press	2014-09-16 13:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-01-18 13:39
Publish the Manuscript Online	2015-01-27 15:33

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Partial embolization as re-treatment of hypersplenism after unsuccessful splenic artery ligation
Manuscript Source	Unsolicited Manuscript
All Author List	Zheng-Ju Xu, Lian-Qiu Zheng and Xing-Nan Pan
Funding Agency and Grant Number
Corresponding Author	Zheng-Ju Xu, Associate Chief Physician, Clinical Liver Center, 180th Hospital of the People’s Liberation Army, No. 180, Huayuan Road, Fengze District, Quanzhou 362000, Fujian Province, China. h180@163.com
Key Words	Hypersplenism; Partial splenic embolization; Splenic artery ligation; Liver cirrhosis; Leukocytopenia; Thrombocytopenia
Core Tip	Ligation of splenic artery (LSA) is used for the treatment of hypersplenism due to liver cirrhosis. However, hypersplenism is not always improved following LSA. We report a case of cirrhosis and hypersplenism which underwent LSA treatment, but failed to respond as manifested by persistent severe leukocytopenia and thrombocytopenia. Celiac computed tomography arteriogram and digital subtraction angiography revealed two compensatory arteries supplying the spleen. Partial splenic embolization (PSE) was performed through those arteries resulting in increased leukocyte and thrombocyte counts that remained within the normal range. PSE is an effective therapeutic modality for the retreatment of hypersplenism when other modalities have failed.
Publish Date	2015-01-27 15:33
Citation	Xu ZJ, Zheng LQ, Pan XN. Partial embolization as re-treatment of hypersplenism after unsuccessful splenic artery ligation. World J Gastroenterol 2015; 21(4): 1365-1370
URL	http://www.wjgnet.com/1007-9327/full/v21/i4/1365.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i4.1365

Full Article (PDF)	WJG-21-1365.pdf
Full Article (Word)	WJG-21-1365.doc
Manuscript File	11940-Review.docx
Answering Reviewers	11940-Answering reviewers.pdf
Copyright License Agreement	11940-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	11940-Language certificate.pdf
Peer-review Report	11940-Peer reviews.pdf
Scientific Misconduct Check	11940-CrossCheck.jpg
Scientific Editor Work List	11940-Scientific editor work list.pdf