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Articles Published Processes
12/12/2014 11:15:00 AM | Browse: 1460 | Download: 1561
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Received |
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2014-06-26 08:24 |
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Peer-Review Started |
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2014-06-26 16:42 |
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To Make the First Decision |
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2014-08-28 15:02 |
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Return for Revision |
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2014-09-01 08:29 |
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Revised |
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2014-09-09 23:58 |
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Second Decision |
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2014-10-10 18:05 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-10-10 18:21 |
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Articles in Press |
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2014-10-10 18:21 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-11-28 17:52 |
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Publish the Manuscript Online |
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2014-12-12 11:14 |
Category |
Infectious Diseases |
Manuscript Type |
Review |
Article Title |
Dried-leaf Artemisia annua: A practical malaria therapeutic for developing countries?
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Manuscript Source |
Invited Manuscript |
All Author List |
Pamela J Weathers, Melissa Towler, Ahmed Hassanali, Pierre Lutgen and Patrick Ogwang Engeu |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Worcester Polytechnic Institute and University of Massachusetts Center for Clinical and Translational Science(in part) |
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National Center for Complementary and Alternative Medicine |
NIH-R15AT008277-01 |
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Corresponding Author |
Pamela J Weathers, Professor, Department of Biology and Biotechnology, Worcester Polytechnic Institute, 100 Institute Rd., Worcester, MA 01609, United States. weathers@wpi.edu |
Key Words |
Malaria; Infectious disease; Artemisia annua; Artemisinin; Combination therapy; Artemisinin combination therapy |
Core Tip |
Artemisinin, extracted from the plant Artemisia annua (A. annua) L., and artemisinin derivatives are the current best antimalarial therapeutics and are delivered as artemisinin combination therapy (ACT). Availability and cost are problematic for the developing world where malaria is endemic. Oral consumption of A. annua dried leaves is more effective than the pure drug. A tea infusion of the leaves has prophylactic effects. Cost of producing and delivering the tea and A. annua dried leaf tablets is much more affordable than ACT. |
Publish Date |
2014-12-12 11:14 |
Citation |
Weathers PJ, Towler M, Hassanali A, Lutgen P, Engeu PO. Dried-leaf Artemisia annua: A practical malaria therapeutic for developing countries? World J Pharmacol 2014; 3(4): 39-55 |
URL |
http://www.wjgnet.com/2220-3192/full/v3/i4/39.htm |
DOI |
http://dx.doi.org/10.5497/wjp.v3.i4.39 |
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