Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	12381
Country	India

Received	2014-07-05 16:18
Peer-Review Started	2014-07-06 15:03
To Make the First Decision	2014-07-18 12:34
Return for Revision	2014-07-18 17:27
Revised	2014-08-15 01:20
Second Decision	2014-09-24 16:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-09-24 16:24
Articles in Press	2014-09-24 16:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-10-31 18:40
Publish the Manuscript Online	2014-11-19 10:25

ISSN	2150-5330 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Management of acute severe ulcerative colitis
Manuscript Source	Invited Manuscript
All Author List	Saurabh Kedia, Vineet Ahuja and Rakesh Tandon
Funding Agency and Grant Number
Corresponding Author	Dr. Rakesh Tandon, Head, Department of Gastroenterology, Pushpawati Singhania Research Institute for Liver, Renal and Digestive Diseases, Press Enclave Marg, Sheikh Sarai II, New Delhi 110017, India. drrakeshtandon@hotmail.com
Key Words	Ulcerative colitis; Acute severe colitis; Intravenous steroids; Cyclosporin; Infliximab
Core Tip	The mortality of severe ulcerative colitis has drastically reduced from 30%-60% in pre steroid era to 1%-2.9% at present. However these figures are for specialist centers and at peripheral centers the mortality figures may be higher. The objective of this review is to provide in depth information for what can be categorized as a gastrointestinal medical emergency with the hope that informed clinical practices may translate to superior patient care at tertiary as well as peripheral centers treating ulcerative colitis. This review provides time bound framework, which looks at stepwise management of acute severe ulcerative colitis and explores the recent concepts of choice between biologics and cyclosporin colon rescue therapies in case of steroid refractory disease.
Publish Date	2014-11-19 10:25
Citation	Kedia S, Ahuja V, Tandon R. Management of acute severe ulcerative colitis. World J Gastrointest Pathophysiol 2014; 5(4): 579-588
URL	http://www.wjgnet.com/2150-5330/full/v5/i4/579.htm
DOI	http://dx.doi.org/10.4291/wjgp.v5.i4.579

Full Article (PDF)	WJGP-5-579.pdf
Full Article (Word)	WJGP-5-579.doc
Manuscript File	12381-Review.docx
Answering Reviewers	12381-Answering reviewers.pdf
Copyright License Agreement	12381-Copyright assignment.pdf
Peer-review Report	12381-Peer review(s).pdf
Scientific Misconduct Check	12381-CrossCheck.jpg
Scientific Editor Work List	12381-Scientific editor work list.pdf