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1/14/2015 11:53:00 AM | Browse: 679 | Download: 946
Publication Name World Journal of Stem Cells
Manuscript ID 12736
Country/Territory United States
Received
2014-07-24 08:45
Peer-Review Started
2014-07-24 16:17
To Make the First Decision
2014-08-28 14:41
Return for Revision
2014-08-29 14:07
Revised
2014-09-03 23:02
Second Decision
2014-09-17 14:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-09-17 14:36
Articles in Press
2014-09-17 14:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-09-24 18:37
Typeset the Manuscript
2014-12-22 11:03
Publish the Manuscript Online
2015-01-14 11:53
ISSN 1948-0210 (online)
Open Access Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Review
Article Title Alternative splicing: An important mechanism in stem cell biology
Manuscript Source Invited Manuscript
All Author List Kenian Chen, Xiaojing Dai and Jiaqian Wu
Funding Agency and Grant Number
Corresponding Author Jiaqian Wu, PhD, The Vivian L Smith Department of Neurosurgery, The Center for Stem Cell and Regenerative Medicine, University of Texas Medical School at Houston, 6431 Fannin St, Houston, TX 77030, United States. jiaqian.wu@uth.tmc.edu
Key Words Alternative splicing; Stem cell; Pluripotency; Differentiation; Splicing factor
Core Tip Alternative splicing (AS) produces multiple transcript isoforms from a single gene, and the regulation of cell-type-specific splicing pattern is crucial for the properties and functions of cells, including pluripotent stem cells. A better understanding of the role of AS in stem cell pluripotency maintenance and differentiation will offer potential new approaches for enhancing the production of induced pluripotent stem cells and/or better control of cell differentiation for research or therapeutic purposes. In this brief review, we provide a timely update of recent studies related to stem cell regulation and splicing in a genome-wide scale.
Publish Date 2015-01-14 11:53
Citation Chen K, Dai X, Wu J. Alternative splicing: An important mechanism in stem cell biology. World J Stem Cells 2015; 7(1): 1-10
URL http://www.wjgnet.com/1948-0210/full/v7/i1/1.htm
DOI http://dx.doi.org/10.4252/wjsc.v7.i1.1
Manuscript File 12736-Review.docx
Answering Reviewers 12736-Answering reviewers.pdf
Copyright License Agreement 12736-Copyright assignment.pdf
Peer-review Report 12736-Peer review(s).pdf
Scientific Misconduct Check 12736-CrossCheck.jpg
Scientific Editor Work List 12736-Scientific editor work list.pdf