Publication Name	World Journal of Stem Cells
Manuscript ID	12785
Country	Japan

Received	2014-07-25 18:07
Peer-Review Started	2014-07-26 23:04
To Make the First Decision	2014-08-14 14:53
Return for Revision	2014-08-14 20:29
Revised	2014-08-29 17:14
Second Decision	2014-09-10 09:16
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-09-10 09:49
Articles in Press	2014-09-10 09:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-09-15 12:55
Publish the Manuscript Online	2014-09-25 12:31

ISSN	1948-0210 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Hematology
Manuscript Type	Review
Article Title	Early B lymphocyte development: Similarities and differences in human and mouse
Manuscript Source	Invited Manuscript
All Author List	Michiko Ichii, Kenji Oritani and Yuzuru Kanakura
Funding Agency and Grant Number
Corresponding Author	Kenji Oritani, MD, Department of Hematology and Oncology, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan. oritani@bldon.med.osaka-u.ac.jp
Key Words	Human B lymphopoiesis; B cell cultures; IL-7; Microenvironment; Wnt signaling
Core Tip	There are several species differences between human and mouse, while the mouse studies precede those of human. Recent progresses of experimental techniques have made it possible to understand the biology in human B lymphopoiesis deeply. Various phenotype markers, which can define the distinct developmental stages, and requirement of cytokines are distinguishable. More common issues are observed in the role of signaling molecules, including transforming growth factor-? superfamily, Wnt family, and Notch family, which have been known the high conservation among mammals. The knowledge on niches for human hematopoietic stem cell and B cell development is still limited.
Publish Date	2014-09-25 12:31
Citation	Ichii M, Oritani K, Kanakura Y. Early B lymphocyte development: Similarities and differences in human and mouse. World J Stem Cells 2014; 6(4): 421-431
URL	http://www.wjgnet.com/1948-0210/full/v6/i4/421.htm
DOI	http://dx.doi.org/10.4252/wjsc.v6.i4.421

Full Article (PDF)	WJSC-6-421.pdf
Full Article (Word)	WJSC-6-421.doc
Manuscript File	12785-Review.docx
Answering Reviewers	12785-Answering reviewers.pdf
Copyright License Agreement	12785-Copyright assignment.pdf
Peer-review Report	12785-Peer review(s).pdf
Scientific Misconduct Check	12785-CrossCheck.jpg
Scientific Editor Work List	12785-Scientific editor work list.pdf