Publication Name	World Journal of Clinical Cases
Manuscript ID	12820
Country

Received	2014-07-27 16:42
Peer-Review Started	2014-07-27 23:28
First Decision by Editorial Office Director
Return for Revision	2014-11-28 16:28
Revised	2014-12-09 19:30
Publication Fee Transferred
Second Decision by Editor	2015-05-29 15:16
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2015-06-08 15:47
Articles in Press	2015-06-08 16:25
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-08-06 16:53
Publish the Manuscript Online	2015-09-15 18:41

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Role of genetic polymorphisms in hepatitis C virus chronic infection
Manuscript Source	Invited Manuscript
All Author List	Nicola Coppola, Mariantonietta Pisaturo, Caterina Sagnelli, Lorenzo Onorato and Evangelista Sagnelli
Funding Agency and Grant Number
Corresponding Author	Dr. Nicola Coppola, Department of Mental Health and Public Medicine, Section of Infectious Diseases, Second University of Naples, Via: L. Armanni 5, 80131 Naples, Italy. nicola.coppola@unina2.it
Key Words	Single nucleotide polymorphism; Hepatitis C virus infection; Interleukin 28B; Inosine triphosphate pyrophosphatase; Patatin-like phospholipase domain-containing protein 3
Core Tip	Some single nucleotide polymorphisms have been associated with the clinical presentation and/or response to antiviral treatment in subjects with chronic hepatitis C (CHC). In this review article the effect of old and new host genetics factors [interleukin 28B, inosine triphosphate pyrophosphatase, patatin-like phospholipase domain, cannabinoid receptor type 2 (CB2-63), vitamin D associated polymorphisms, etc.] on the outcome of CHC and the response to antiviral treatment will be presented, analyzed and discussed, to provide some guidance for individualized therapies in clinical practice.
Publish Date	2015-09-15 18:41
Citation	Coppola N, Pisaturo M, Sagnelli C, Onorato L, Sagnelli E. Role of genetic polymorphisms in hepatitis C virus chronic infection. World J Clin Cases 2015; 3(9): 807-822
URL	http://www.wjgnet.com/2307-8960/full/v3/i9/807.htm
DOI	http://dx.doi.org/10.12998/wjcc.v3.i9.807

Full Article (PDF)	WJCC-3-807.pdf
Full Article (Word)	WJCC-3-807.doc
Manuscript File	12820-Review.docx
Answering Reviewers	12820-Answering reviewers.pdf
Audio Core Tip	12820-Audio core tip.3ga
Conflict-of-Interest Disclosure Form	12820-Conflict-of-interest statement.pdf
Copyright License Agreement	12820-Copyright assignment.pdf
Peer-review Report	12820-Peer-review(s).pdf
Scientific Misconduct Check	12820-Scientific misconduct check.pdf
Scientific Editor Work List	12820-Scientific editor work list.pdf