Publication Name	World Journal of Stem Cells
Manuscript ID	12916
Country	Iran

Received	2014-07-29 09:14
Peer-Review Started	2014-07-29 22:49
To Make the First Decision	2014-09-28 13:59
Return for Revision	2014-09-29 18:50
Revised	2014-12-10 03:10
Second Decision	2014-12-23 20:19
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-12-31 13:32
Articles in Press	2014-12-31 13:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-03-30 17:26
Publish the Manuscript Online	2015-04-23 12:08

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Dentistry, Oral Surgery & Medicine
Manuscript Type	Systematic Reviews
Article Title	Smart scaffolds in bone tissue engineering: A systematic review of literature
Manuscript Source	Invited Manuscript
All Author List	Saeed Reza Motamedian, Sepanta Hosseinpour, Mitra Ghazizadeh Ahsaie and Arash Khojasteh
Funding Agency and Grant Number
Corresponding Author	Arash Khojasteh, DMD, MS, Department of Oral and Maxillofacial Surgery, School of Dentistry, Shahid Beheshti University of Medical Sciences, Daneshjou Boulevard, Evin, Tehran PO Box 19839, Iran. arashkhojasteh@yahoo.com
Key Words	Bone tissue engineering; Scaffold; Growth factor; Nanoparticle; Extracellular matrix
Core Tip	Currently, special attention has been directed to the design of new scaffolds by adding bioactive molecules and nanoparticles. “Smart scaffolds” in bone tissue engineering not only act as cell delivery materials, but they are also responsive to their environment and therefore stem cells are more likely to attach, proliferate and differentiate on them. These scaffolds can be fabricated by adding either of growth factors, extracellular matrix proteins or nanoparticles to the bone substitutes using various techniques. These modifications can enhance the in vitro response of bone scaffolds toward cells.
Publish Date	2015-04-23 12:08
Citation	Motamedian SR, Hosseinpour S, Ahsaie MG, Khojasteh A. Smart scaffolds in bone tissue engineering: A systematic review of literature. World J Stem Cells 2015; 7(3): 657-668
URL	http://www.wjgnet.com/1948-0210/full/v7/i3/657.htm
DOI	http://dx.doi.org/10.4252/wjsc.v7.i3.657

Full Article (PDF)	WJSC-7-657.pdf
Full Article (Word)	WJSC-7-657.doc
Manuscript File	12916-Review.docx
Answering Reviewers	12916-Answering reviewers.pdf
Biostatistics Review Certificate	12916-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	12916-Conflict-of-interest statement.pdf
Copyright License Agreement	12916-Copyright assignment.pdf
Peer-review Report	12916-Peer review(s).pdf
Scientific Misconduct Check	12916-CrossCheck.jpg
Scientific Editor Work List	12916-Scientific editor work list.pdf