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Articles Published Processes
1/14/2015 11:53:00 AM | Browse: 1122 | Download: 1424
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Received |
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2014-07-30 09:31 |
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Peer-Review Started |
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2014-07-31 18:01 |
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To Make the First Decision |
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2014-09-16 10:48 |
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Return for Revision |
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2014-09-18 13:56 |
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Revised |
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2014-10-06 20:28 |
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Second Decision |
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2014-10-27 16:49 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-10-27 17:07 |
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Articles in Press |
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2014-10-27 17:07 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-12-22 16:25 |
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Publish the Manuscript Online |
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2015-01-14 11:53 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Nanoscience & Nanotechnology |
| Manuscript Type |
Review |
| Article Title |
Mesenchymal stem cell tracking in the intervertebral disc
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Charles Handley, Tony Goldschlager, David Oehme, Peter Ghosh and Graham Jenkin |
| Funding Agency and Grant Number |
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| Corresponding Author |
Charles Handley, MBBS, The Ritchie Centre, Monash Institute of Medical Research, Monash University, Wellington Road, Clayton VIC 3168, Australia. charles.handley@monashhealth.org |
| Key Words |
Intervertebral disc; Stem cells; Cell tracking; Magnetic resonance imaging; Intervertebral disc degeneration |
| Core Tip |
Mesenchymal stem cell (MSC) transplantation shows exciting promise for the future regenerative approach to intervertebral disc (IVD) disease. Extensive preclinical research has demonstrated benefits from MSC treatment in disc degeneration. Cell tracking, with iron oxide nanoparticles and MRI, provides an opportunity to develop an in-depth understanding of stem cell survival, differentiation and migration, enabling optimization of stem cell treatment. This review summarizes the current literature relating to MSC tracking in the IVD, which is limited to short term monitoring. Medium to long-term cell tracking is required to accelerate translation of MSC treatment in the IVD to clinical practice. |
| Publish Date |
2015-01-14 11:53 |
| Citation |
Handley C, Goldschlager T, Oehme D, Ghosh P, Jenkin G. Mesenchymal stem cell tracking in the intervertebral disc. World J Stem Cells 2015; 7(1): 65-74 |
| URL |
http://www.wjgnet.com/1948-0210/full/v7/i1/65.htm |
| DOI |
http://dx.doi.org/10.4252/wjsc.v7.i1.65 |
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