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3/9/2015 3:58:00 PM | Browse: 615 | Download: 693
Publication Name World Journal of Gastroenterology
Manuscript ID 13109
Country/Territory United States
2014-08-06 08:34
Peer-Review Started
2014-08-06 16:58
To Make the First Decision
2014-09-15 16:12
Return for Revision
2014-09-22 08:23
2014-10-18 13:51
Second Decision
2014-11-27 21:35
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-12-01 13:46
Articles in Press
2014-12-01 14:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-02-11 21:22
Publish the Manuscript Online
2015-03-09 15:58
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Report
Article Title Pancreatic intraductal papillary mucinous neoplasm in a patient with Lynch syndrome
Manuscript Source Unsolicited Manuscript
All Author List Meghan R Flanagan, Arjun Jayaraj, Wei Xiong, Matthew M Yeh, Wendy H Raskind and Venu G Pillarisetty
Funding Agency and Grant Number
Funding Agency Grant Number
University of Washington Department of Surgery, Seattle, WA
Corresponding author Venu G Pillarisetty, MD, Assistant Professor, Department of Surgery, University of Washington Medical Center, University of Washington, 1959 NE Pacific St. Box 356410, Seattle, WA 98195, United States. vgp@uw.edu
Keywords Intraductal papillary mucinous neoplasm; Pancreatic cancer; Hereditary nonpolyposis colorectal cancer; Lynch syndrome; MSH2; Microsatellite instability
Core Tip Intraductal papillary mucinous neoplasms (IPMN) are now recognized as important precursor lesions to pancreatic cancer. Although there have been reports linking pancreatic cancer and familial cancer syndromes, only one previous case report has described IPMN in a patient with Lynch syndrome. Our case is a main duct IPMN that contained only low-grade dysplasia and no microsatellite instability despite the presence of a germline MSH2 mutation. Mismatch repair (MMR) gene mutations may be involved in the neoplastic changes that drive the development of IPMN; however, changes in MMR function may not be detectable in the setting of low-grade neoplasia.
Publish Date 2015-03-09 15:58
Citation Flanagan MR, Jayaraj A, Xiong W, Yeh MM, Raskind WH, Pillarisetty VG. Pancreatic intraductal papillary mucinous neoplasm in a patient with Lynch syndrome. World J Gastroenterol 2015; 21(9): 2820-2825
Url http://www.wjgnet.com/1007-9327/full/v21/i9/2820.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i9.2820
Full Article (PDF) WJG-21-2820.pdf
Full Article (Word) WJG-21-2820.doc
Manuscript File 13109-Review.docx
Answering Reviewers 13109-Answering reviewers.pdf
Copyright License Agreement 13109-Copyright assignment.pdf
Peer-review Report 13109-Peer review(s).pdf
Scientific Misconduct Check 13109-CrossCheck.jpg
Scientific Editor Work List 13109-Scientific editor work list.pdf