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Articles Published Processes
4/23/2015 12:08:00 PM | Browse: 1203 | Download: 1626
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Received |
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2014-08-12 09:28 |
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Peer-Review Started |
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2014-08-13 19:35 |
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To Make the First Decision |
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2014-10-28 14:22 |
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Return for Revision |
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2014-11-03 09:06 |
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Revised |
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2014-11-10 23:20 |
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Second Decision |
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2014-12-11 08:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-12-17 16:45 |
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Articles in Press |
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2014-12-17 16:45 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-03-30 11:32 |
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Publish the Manuscript Online |
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2015-04-23 12:08 |
ISSN |
1948-0210 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Review |
Article Title |
New insights into pancreatic cancer stem cells
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Manuscript Source |
Invited Manuscript |
All Author List |
Chinthalapally V Rao and Altaf Mohammed |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Kerley Cade Endowed Chair, University of Oklahoma Health Sciences Center |
to Chinthalapally V Rao(In part) |
National Cancer Institute |
5R03CA181584-02(to Altaf Mohammed, In part) |
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Corresponding Author |
Altaf Mohammed, PhD, Center for Cancer Prevention and Drug Development, Department of Medicine, Hematology-Oncology Section, PC Stephenson Cancer Center, University of Oklahoma Health Sciences Center, 975 NE 10th Street, BRC II, Room 1209B, Oklahoma City, OK 73104, United States. amohamme@ouhsc.edu |
Key Words |
Pancreatic cancer; Cancer stem cells; DclK1; Lgr5; Prevention; Treatment |
Core Tip |
Despite aggressive treatment modalities, pancreatic cancer represents most lethal malignancy with uniform lethality. The pancreatic cancer stem cells (CSCs) have been found to be resistant to chemotherapy and radiation therapy. This review summarizes the important role of CSCs in pancreatic cancer tumor progression with emphasis on DclK1 and Lgr5 CSCs, molecular signaling altered by CSCs and the important role of pancreatic CSCs in prevention and treatment of pancreatic cancer. |
Publish Date |
2015-04-23 12:08 |
Citation |
Rao CV, Mohammed A. New insights into pancreatic cancer stem cells. World J Stem Cells 2015; 7(3): 547-555 |
URL |
http://www.wjgnet.com/1948-0210/full/v7/i3/547.htm |
DOI |
http://dx.doi.org/10.4252/wjsc.v7.i3.547 |
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