Publication Name	World Journal of Hepatology
Manuscript ID	13431
Country	Japan

Received	2014-08-22 18:03
Peer-Review Started	2014-08-23 11:26
To Make the First Decision	2014-09-28 12:32
Return for Revision	2014-10-08 14:18
Revised	2014-10-20 17:33
Second Decision	2014-12-25 18:07
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-12-31 13:17
Articles in Press	2014-12-31 13:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-03-20 12:16
Publish the Manuscript Online	2015-03-31 15:58

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Prevention of hepatocellular carcinoma: Focusing on antioxidant therapy
Manuscript Source	Invited Manuscript
All Author List	Koji Miyanishi, Toshifumi Hoki, Shingo Tanaka and Junji Kato
Funding Agency and Grant Number
Corresponding Author	Koji Miyanishi, MD, PhD, Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-Ku, Sapporo 060-8543, Japan. miyako@sapmed.ac.jp
Key Words	Chronic hepatitis; Antioxidant therapy; Hepatocellular carcinoma; Prevention; Iron depletion therapy
Core Tip	Among treatment options where it would be expected that anti-inflammatory activity plays a role in their confirmed efficacy for chronic hepatitis, iron depletion therapy, glycyrrhizin, ursodeoxycholic acid, Sho-Saiko-To, and vitamin E can all be considered antioxidant therapies. In chronic liver diseases, it has been demonstrated that antioxidant therapy may potentially be effective for suppressing inflammation and liver fibrosis and expected to prevent carcinogenesis.
Publish Date	2015-03-31 15:58
Citation	Miyanishi K, Hoki T, Tanaka S, Kato J. Prevention of hepatocellular carcinoma: Focusing on antioxidant therapy. World J Hepatol 2015; 7(3): 593-599
URL	http://www.wjgnet.com/1948-5182/full/v7/i3/593.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i3.593

Full Article (PDF)	WJH-7-593.pdf
Full Article (Word)	WJH-7-593.doc
Manuscript File	13431-Review.docx
Answering Reviewers	13431-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	13431-Conflict-of-interest statement.pdf
Copyright License Agreement	13431-Copyright assignment.pdf
Peer-review Report	13431-Peer review(s).pdf
Scientific Misconduct Check	13431-CrossCheck.jpg
Scientific Editor Work List	13431-Scientific editor work list.pdf