Publication Name	World Journal of Virology
Manuscript ID	1366
Country	Italy

Received	2012-12-05 09:46
Peer-Review Started	2012-12-05 18:17
To Make the First Decision	2013-01-17 11:00
Return for Revision	2013-01-17 19:38
Revised	2013-04-04 02:28
Second Decision	2013-04-10 17:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-04-11 05:43
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-04-16 14:26
Publish the Manuscript Online	2013-05-09 13:09

ISSN	2220-3249 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Topic Highlights
Article Title	How virus persistence can initiate the tumorigenesis process
Manuscript Source	Invited Manuscript
All Author List	Simone Avanzi, Gualtiero Alvisi and Alessandro Ripalti
Funding Agency and Grant Number
Corresponding Author	Dr. Alessandro Ripalti, Department of Oncology, Hematology and Laboratory Medicine, Operative Unit of Microbiology, A.O-U. di Bologna Policlinico S. Orsola-Malpighi, via Massarenti 9, 40138 Bologna, Italy. alessandro.ripalti@unibo.it
Key Words	Virus; Carcinogenesis; Tumor; Oncogene; Latency; Viral persistence
Core Tip	Current models for viral driven oncogenesis cannot explain why tumor development in carriers of tumorigenic viruses is a very rare event, occurring decades after virus infection. Considering that viruses are mutagenic agents per se and human oncogenic viruses additionally establish latent and persistent infections, we attempt here to provide a general mechanism of tumor initiation both for RNA and DNA viruses, suggesting viruses could be both necessary and sufficient in triggering human tumorigenesis initiation.
Publish Date	2013-05-09 13:09
Citation	Avanzi S, Alvisi G, Ripalti A. How virus persistence can initiate the tumorigenesis process. World J Virol 2013; 2(2): 102-109
URL	http://www.wjgnet.com/2220-3249/full/v2/i2/102.htm
DOI	http://dx.doi.org/10.5501/wjv.v2.i2.102

Full Article (PDF)	WJV-2-102.pdf
Manuscript File	1366-Review.docx
Answering Reviewers	1366-Answering reviewers.docx
Copyright License Agreement	1366-Copyright assignment.pdf
Peer-review Report	1366-Peer review(s).pdf
Scientific Editor Work List	1366-Scientific editor work list.doc