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1/10/2015 4:31:00 PM | Browse: 420 | Download: 407
Publication Name World Journal of Hepatology
Manuscript ID 13690
Country of Manuscript Source Italy
Received
2014-08-29 09:25
Peer-Review Started
2014-08-30 11:54
To Make the First Decision
2014-09-28 12:24
Return for Revision
2014-09-30 16:50
Revised
2014-10-10 04:13
Second Decision
2014-11-12 14:13
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-11-19 10:49
Articles in Press
2014-11-19 10:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-12-26 14:42
Publish the Manuscript Online
2015-01-10 16:31
ISSN 1948-5182 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7901 Stoneridge Drive, Suite 501, Pleasanton, CA 94588, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Topic Highlights
Article Title Assessment of clinical and radiological response to sorafenib in hepatocellular carcinoma patients
Manuscript Source Invited Manuscript
All Author List Rodolfo Sacco, Valeria Mismas, Antonio Romano, Marco Bertini, Michele Bertoni, Graziana Federici, Salvatore Metrangolo, Giuseppe Parisi, Emanuele Tumino, Giampaolo Bresci, Luca Giacomelli, Sara Marceglia and Irene Bargellini
Funding Agency and Grant Number
Correspondence To Rodolfo Sacco, MD, PhD, Dipartimento di Gastroenterologia-UO Gastroenterologia e Malattie del Ricambio, Azienda Ospedaliero Universitaria Pisana, Via Paradisa 2, 56124 Pisa, Italy. r.sacco@ao-pisa.toscana.it
Keywords Hepatocellular carcinoma; Sorafenib; Re­sponse Evaluation Criteria in Solid Tumors; Perfusion computed tomography; Dynamic Contrast-Enhanced-UltraSound; Volumetric assessment
Core Tip The development of new treatment options for hepatocellular carcinoma has changed not only the way in which cancer is treated, but also how it is diagnosed and especially the assessment of tumor response. The traditional radiologic methods, which are mainly based on the evaluation of variations in tumor size, are considered insufficiently sensitive and unreliable in determining tumor progression when targeted therapies like sorafenib are involved. New assessment tools trying to combine morphological and vascular functional data to obtain an accurate measurement of tumor characteristics such as volume, density or vascularization, showed positive results in assessing patient’s response to therapy.
Publish Date 2015-01-10 16:31
Citation Sacco R, Mismas V, Romano A, Bertini M, Bertoni M, Federici G, Metrangolo S, Parisi G, Tumino E, Bresci G, Giacomelli L, Marceglia S, Bargellini I. Assessment of clinical and radiological response to sorafenib in hepatocellular carcinoma patients. World J Hepatol 2015; 7(1): 33-39
Url http://www.wjgnet.com/1948-5182/full/v7/i1/33.htm
DOI http://dx.doi.org/10.4254/wjh.v7.i1.33
Full Article (PDF) WJH-7-33.pdf
Full Article (Word) WJH-7-33.doc
Revised Manuscript 13690-Review.docx
Peer-review Report 13690-Peer review(s).pdf
Answering Reviewers 13690-Answering reviewers.pdf
Scientific Misconduct Check 13690-CrossCheck.jpg
Scientific Editor Work List 13690-Scientific editor work list.pdf
Copyright License Agreement 13690-Copyright assignment.pdf