Publication Name	World Journal of Diabetes
Manuscript ID	13753
Country	United Kingdom

Received	2014-08-30 16:54
Peer-Review Started	2014-08-30 17:33
To Make the First Decision	2014-12-17 11:36
Return for Revision	2014-12-21 17:48
Revised	2015-01-01 03:24
Second Decision	2015-02-04 11:59
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-03-09 16:37
Articles in Press	2015-03-09 16:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-06-28 14:57
Publish the Manuscript Online	2015-07-10 18:24

ISSN	1948-9358 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Biochemistry & Molecular Biology
Manuscript Type	Review
Article Title	Metabolic syndrome: A review of the role of vitamin D in mediating susceptibility and outcome
Manuscript Source	Invited Manuscript
All Author List	Richard C Strange, Kate E Shipman and Sudarshan Ramachandran
Funding Agency and Grant Number
Corresponding Author	Dr. Sudarshan Ramachandran, Depart­ment of Clinical Biochemistry, Good Hope Hospital, Heart of England NHS Foundation Trust, Rectory Road, Sutton Coldfield B75 7RR, United Kingdom. sud.ramachandran@heartofengland.nhs.uk
Key Words	Vitamin D; Hypovitaminosis D; Metabolic syndrome; Type 2 diabetes mellitus; Insulin resistance; Cardiovascular disease; Atherogenic dyslipidaemia; Hypertension; Non-alcoholic fatty liver disease
Core Tip	The metabolic syndrome is common, affecting about 40% of Americans. It is defined by combinations of risk factors for cardiovascular disease (CVD) including insulin resistance and abdominal obesity. Research implicates hypovitaminosis D in the causation and phenotype of the syndrome and we present relevant data. While hypovitaminosis appears a risk factor for components of the syndrome and its outcome, the mechanism is unclear. The risks associated with varying levels of hypovitaminosis and the benefits of vitamin replacement are unknown. However, unravelling the association between hypovitaminosis and the syndrome is warranted as even a modest decrease in CVD risk would confer substantial benefits.
Publish Date	2015-07-10 18:24
Citation	Strange RC, Shipman KE, Ramachandran S. Metabolic syndrome: A review of the role of vitamin D in mediating susceptibility and outcome. World J Diabetes 2015; 6(7): 896-911
URL	http://www.wjgnet.com/1948-9358/full/v6/i7/896.htm
DOI	http://dx.doi.org/10.4239/wjd.v6.i7.896

Full Article (PDF)	WJD-6-896.pdf
Full Article (Word)	WJD-6-896.doc
Manuscript File	13753-Review.docx
Answering Reviewers	13753-Answering rewiewers.pdf
Conflict-of-Interest Disclosure Form	13753-Conflict-of-interest statement.pdf
Copyright License Agreement	13753-Copyright assignment.pdf
Peer-review Report	13753-Peer-review(s).pdf
Scientific Misconduct Check	13753-Scientific misconduct check.pdf
Scientific Editor Work List	13753-Scientific editor work list.pdf