Publication Name	World Journal of Diabetes
Manuscript ID	13839
Country	Hungary

Received	2014-09-03 17:35
Peer-Review Started	2014-09-04 11:19
To Make the First Decision	2014-11-14 19:40
Return for Revision	2014-11-19 15:54
Revised	2014-12-05 23:12
Second Decision	2014-12-29 18:27
Accepted by Journal Editor-in-Chief	2014-12-30 03:31
Accepted by Executive Editor-in-Chief	2015-01-12 14:24
Articles in Press	2015-01-12 14:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-04-09 16:10
Publish the Manuscript Online	2015-04-20 09:13

ISSN	1948-9358 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Endocrinology & Metabolism
Manuscript Type	Minireviews
Article Title	Tyrosine isomers and hormonal signaling: A possible role for the hydroxyl free radical in insulin resistance
Manuscript Source	Invited Manuscript
All Author List	Gergő A Molnár, Esztella Zsóka Mikolás, István András Szijártó, Szilárd Kun, Eszter Sélley and István Wittmann
Funding Agency and Grant Number	Funding Agency Grant Number European Social Fund in the framework of TÁMOP 4.2.4. A/2-11-1-2012-0001 National Excellence Program
Corresponding Author	István Wittmann, MD, PhD, Professor of Medicine, Head of the Department, 2nd Department of Medicine and Nephrological Center, University of Pécs, Pacsirta Str. 1, H-7624 Pécs, Hungary. istvan.wittmann@aok.pte.hu
Key Words	Acetylcholine; Insulin resistance; Hormone resistance; Oxidative stress; Para-tyrosine; Ortho-tyrosine; Meta-tyrosine; Erythropoietin
Core Tip	Hydroxyl-free radical-derived amino acids, such as meta- and ortho-tyrosine (m- and o-Tyr, respectively) are regarded as free radical markers, but they may also be taken up and incorporated into blood vessel walls, erythroid precursors and endothelial cells. These pathological amino acids can induce vascular insulin and acetylcholine, as well as cellular erythropoietin resistance.
Publish Date	2015-04-20 09:13
Citation	Molnár GA, Mikolás EZ, Szijártó IA, Kun S, Sélley E, Wittmann I. Tyrosine isomers and hormonal signaling: A possible role for the hydroxyl free radical in insulin resistance. World J Diabetes 2015; 6(3): 500-507
URL	http://www.wjgnet.com/1948-9358/full/v6/i3/500.htm
DOI	http://dx.doi.org/10.4239/wjd.v6.i3.500

Full Article (PDF)	WJD-6-500.pdf
Full Article (Word)	WJD-6-500.doc
Manuscript File	13839-Review.doc
Answering Reviewers	13839-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	13839-Conflict-of-interest statement.pdf
Copyright License Agreement	13839-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	13839-Language certificate.pdf
Peer-review Report	13839-Peer review(s).pdf
Scientific Misconduct Check	13839-CrossCheck.jpg
Scientific Editor Work List	13839-Scientific editor work list.pdf