Publication Name	World Journal of Gastroenterology
Manuscript ID	13901
Country	China

Received	2014-09-06 11:34
Peer-Review Started	2014-09-07 18:58
First Decision by Editorial Office Director
Return for Revision	2014-10-20 09:50
Revised	2014-11-15 15:00
Publication Fee Transferred
Second Decision by Editor	2015-01-23 16:31
Second Decision by Editor-in-Chief	2015-01-26 08:59
Final Decision by Editorial Office Director	2015-01-30 15:34
Articles in Press	2015-01-30 18:29
Edit the Manuscript by Language Editor	2015-02-04 23:43
Typeset the Manuscript	2015-03-19 17:52
Publish the Manuscript Online	2015-04-07 17:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Antiviral therapies for hepatitis B virus-related hepatocellular carcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Yuan-Qing Zhang and Jin-Sheng Guo
Funding Agency and Grant Number	Funding Agency Grant Number National Fund of Nature Science of China 30570825 National Fund of Nature Science of China 81070340 National Fund of Nature Science of China 91129705
Corresponding Author	Jin-Sheng Guo, MD, Division of Digestive Diseases, Department of Internal Medicine, Zhong Shan Hospital, Shanghai Medical College, Fu Dan University, 180 Feng Lin Road, Shanghai 200032, China. guo.jinsheng@zs-hospital.sh.cn
Key Words	Chronic hepatitis B; Hepatocellular carcinoma; Antiviral therapy
Core Tip	This review provides an overview of recent studies and practice guidelines on antiviral treatments for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) and emphasizes their significance. HBV infection promotes HCC development by inducing liver fibrogenesis, genetic and epigenetic alterations, and the expression of active viral-coded proteins. Timely initiation of antiviral treatment is not only essential for preventing the incidence of HCC in chronic hepatitis B patients, but also important for reducing HBV reactivation, improving liver function, reducing or delaying HCC recurrence, and prolonging overall survival of HBV-related HCC patients after curative and palliative therapies.
Publish Date	2015-04-07 17:13
Citation	Zhang YQ, Guo JS. Antiviral therapies for hepatitis B virus-related hepatocellular carcinoma. World J Gastroenterol 2015; 21(13): 3860-3866
URL	http://www.wjgnet.com/1007-9327/full/v21/i13/3860.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i13.3860

Full Article (PDF)	WJG-21-3860.pdf
Full Article (Word)	WJG-21-3860.doc
Manuscript File	13901-Reivew.docx
Answering Reviewers	13901-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	13901-Conflict-of-interest statement.pdf
Copyright License Agreement	13901-Copyright assignment.pdf
Peer-review Report	13901-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	13901-Journal Editor-in-Chief's Review Report.pdf
Scientific Misconduct Check	13901-CrossCheck.jpg
Scientific Editor Work List	13901-Scientific editor work list.pdf