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Articles Published Processes
1/7/2015 11:06:00 AM | Browse: 1358 | Download: 1318
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Received |
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2014-09-09 08:02 |
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Peer-Review Started |
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2014-09-09 14:06 |
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To Make the First Decision |
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2014-10-14 16:59 |
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Return for Revision |
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2014-10-15 17:23 |
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Revised |
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2014-10-29 06:25 |
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Second Decision |
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2014-11-11 09:39 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-11-19 09:12 |
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Articles in Press |
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2014-11-19 09:40 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-12-25 11:40 |
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Publish the Manuscript Online |
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2015-01-07 11:07 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Basic Study |
Article Title |
Altered vasoactive intestinal peptides expression in irritable bowel syndrome patients and rats with trinitrobenzene sulfonic acid-induced colitis
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Arseima Y Del Valle-Pinero, LeeAnne B Sherwin, Ethan M Anderson, Robert M Caudle and Wendy A Henderson |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Institutes of Health grant |
NS045614 |
Ruth L. Kirschstein National Research Service Award |
1F31 DK083165-01A1 |
Division of Intramural Research, National Institute of Nursing Research |
1ZIANR000018-01-05(to Henderson WA) |
Intramural Training Award |
to Del Valle-Pinero AY and Sherwin LB |
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Corresponding Author |
Dr. Wendy A Henderson, PhD, Chief, Digestive Disorders Unit, Biobehavioral Branch, Division of Intramural Research, National Institute of Nursing Research, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, United States. hendersw@mail.nih.gov |
Key Words |
Irritable bowel syndrome; Vasoactive intestinal peptide; Trinitrobenzene sulfonic acid; Gene expression; PCR arrays |
Core Tip |
The present study reports evidence of altered vasoactive intestinal peptide (VIP) in both humans with irritable bowel syndrome (IBS) and a rat model with induced colitis by trinitrobenzene sulfonic acid. Together these observations provide additional evidence of the role of VIP, and the potential therapeutic application in patients with IBS. The results provide a basis for future studies to elucidate the understanding of the expression, physiology, and pharmacological properties of VIP. |
Publish Date |
2015-01-07 11:07 |
Citation |
Del Valle-Pinero AY, Sherwin LB, Anderson EM, Caudle RM, Henderson WA. Altered vasoactive intestinal peptides expression in irritable bowel syndrome patients and rats with trinitrobenzene sulfonic acid-induced colitis. World J Gastroenterol 2015; 21(1): 155-163 |
URL |
http://www.wjgnet.com/1007-9327/full/v21/i1/155.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v21.i1.155 |
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